Transcription Factors, TFII
"Transcription Factors, TFII" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The so-called general transcription factors that bind to RNA POLYMERASE II and that are required to initiate transcription. They include TFIIA; TFIIB; TFIID; TFIIE; TFIIF; TFIIH; TFII-I; and TFIIJ. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme.
Descriptor ID |
D019473
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MeSH Number(s) |
D12.776.260.775.875 D12.776.930.930.875
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factors, TFII".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factors, TFII".
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Year | Major Topic | Minor Topic | Total |
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2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factors, TFII" by people in Profiles.
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Structural basis of RNA polymerase III transcription initiation. Nature. 2018 01 17; 553(7688):301-306.