Histamine H1 Antagonists, Non-Sedating
"Histamine H1 Antagonists, Non-Sedating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.
| Descriptor ID |
D039563
|
| MeSH Number(s) |
D27.505.519.625.375.425.400.500 D27.505.696.577.375.425.400.500
|
| Concept/Terms |
Histamine H1 Antagonists, Non-Sedating- Histamine H1 Antagonists, Non-Sedating
- Histamine H1 Antagonists, Non Sedating
- Second Generation H1 Antagonists
- H1 Antihistamines, Non-Sedating
- H1 Antihistamines, Non Sedating
- Non-Sedating H1 Antihistamines
- Second Generation Antihistamines
- Antihistamines, Second Generation
|
Below are MeSH descriptors whose meaning is more general than "Histamine H1 Antagonists, Non-Sedating".
Below are MeSH descriptors whose meaning is more specific than "Histamine H1 Antagonists, Non-Sedating".
This graph shows the total number of publications written about "Histamine H1 Antagonists, Non-Sedating" by people in this website by year, and whether "Histamine H1 Antagonists, Non-Sedating" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Histamine H1 Antagonists, Non-Sedating" by people in Profiles.
-
Azelastine inhibits viropexis of SARS-CoV-2 spike pseudovirus by binding to SARS-CoV-2 entry receptor ACE2. Virology. 2021 08; 560:110-115.
-
Testing of the inhibitory effects of loratadine and desloratadine on SARS-CoV-2 spike pseudotyped virus viropexis. Chem Biol Interact. 2021 Apr 01; 338:109420.
-
Urticaria as a first clinical manifestation of COVID-19. Eur J Dermatol. 2020 Dec 01; 30(6):737-738.
-
Reposition of montelukast either alone or in combination with levocetirizine against SARS-CoV-2. Med Hypotheses. 2020 Nov; 144:110046.
-
Mask-induced contact dermatitis in handling COVID-19 outbreak. Contact Dermatitis. 2020 08; 83(2):166-167.
-
Antihistamines for Allergic Rhinitis Treatment from the Viewpoint of Nonsedative Properties. Int J Mol Sci. 2019 Jan 08; 20(1).
-
Real life management of chronic urticaria: Multicenter and cross sectional study on patients and dermatologists in Iran. Dermatol Ther. 2019 03; 32(2):e12796.
-
Efficacy of Omalizumab Treatment with Concomitant Antihistamines as Needed for Moderate, Refractory Chronic Spontaneous Urticaria. Acta Derm Venereol. 2018 Apr 16; 98(4):446-448.
-
Salt-dependent aquagenic urticaria in children: Report of two cases. Pediatr Allergy Immunol. 2018 05; 29(3):324-326.
-
Efficacy of desloratadine in persistent allergic rhinitis - a GA²LEN study. Int Arch Allergy Immunol. 2010; 153(4):395-402.