"B7-1 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
Descriptor ID |
D018122
|
MeSH Number(s) |
D12.776.467.150.100 D12.776.543.095.100 D23.050.301.285.100 D23.529.168.100
|
Concept/Terms |
B7-1 Antigen- B7-1 Antigen
- B7 1 Antigen
- CD80 Antigen
- CD80 Antigens
- B7-1 Ligand
- B7 1 Ligand
- Ligand, B7-1
- B7-1 Costimulatory Molecule
- B7 1 Costimulatory Molecule
- Costimulatory Molecule, B7-1
- Antigen, B7-1
- Antigen, B7 1
- B-Cell Activation Antigen
- B Cell Activation Antigen
- Antigens, CD80
|
Below are MeSH descriptors whose meaning is more general than "B7-1 Antigen".
Below are MeSH descriptors whose meaning is more specific than "B7-1 Antigen".
This graph shows the total number of publications written about "B7-1 Antigen" by people in this website by year, and whether "B7-1 Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2000 | 1 | 0 | 1 |
2003 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2017 | 0 | 6 | 6 |
2018 | 2 | 1 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "B7-1 Antigen" by people in Profiles.
-
Spike protein of SARS-CoV-2 activates macrophages and contributes to induction of acute lung inflammation in male mice. FASEB J. 2021 09; 35(9):e21801.
-
Targeting of the CD80/86 proinflammatory axis as a therapeutic strategy to prevent severe COVID-19. Sci Rep. 2021 06 01; 11(1):11462.
-
The role of B7-1 in proteinuria of glomerular origin. Nat Rev Nephrol. 2018 09; 14(9):589-596.
-
SslE (YghJ), a Cell-Associated and Secreted Lipoprotein of Neonatal Septicemic Escherichia coli, Induces Toll-Like Receptor 2-Dependent Macrophage Activation and Proinflammation through NF-?B and MAP Kinase Signaling. Infect Immun. 2018 09; 86(9).
-
Identification of another primordial CD80/86 molecule in rainbow trout: Insights into the origin and evolution of CD80 and CD86 in vertebrates. Dev Comp Immunol. 2018 12; 89:73-82.
-
Diversification of human plasmacytoid predendritic cells in response to a single stimulus. Nat Immunol. 2018 Jan; 19(1):63-75.
-
Characterisation of the immune-related transcriptome in resected biliary tract cancers. Eur J Cancer. 2017 11; 86:158-165.
-
Sinulariolide suppresses LPS-induced phenotypic and functional maturation of dendritic cells. Mol Med Rep. 2017 Nov; 16(5):6992-7000.
-
Dendritic cells activation is associated with sustained virological response to telaprevir treatment of HCV-infected patients. Clin Immunol. 2017 10; 183:82-90.
-
Montelukast improves the changes of cytoskeletal and adaptor proteins of human podocytes by interleukin-13. Inflamm Res. 2017 Sep; 66(9):793-802.