"Compassionate Use Trials" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Providing an investigational therapy to a patient who is not eligible to receive that therapy in a clinical trial, but who has a serious or life-threatening illness for which other treatments are not available. Compassionate use trials allow patients to receive promising but not yet fully studied or approved therapies when no other treatment option exists. Also called expanded access trial.
Descriptor ID |
D057176
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MeSH Number(s) |
E02.931.500 E05.337.300.199
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Concept/Terms |
Compassionate Use Trials- Compassionate Use Trials
- Compassionate Use Trial
- Trial, Compassionate Use
- Trials, Compassionate Use
- Use Trials, Compassionate
- Expanded Access Trials
- Access Trial, Expanded
- Expanded Access Trial
- Trial, Expanded Access
- Trials, Expanded Access
Humanitarian Device Exemption- Humanitarian Device Exemption
- Device Exemption, Humanitarian
- Device Exemptions, Humanitarian
- Exemption, Humanitarian Device
- Exemptions, Humanitarian Device
- Humanitarian Device Exemptions
|
Below are MeSH descriptors whose meaning is more general than "Compassionate Use Trials".
Below are MeSH descriptors whose meaning is more specific than "Compassionate Use Trials".
This graph shows the total number of publications written about "Compassionate Use Trials" by people in this website by year, and whether "Compassionate Use Trials" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2017 | 2 | 7 | 9 |
2018 | 4 | 5 | 9 |
2019 | 5 | 3 | 8 |
2020 | 12 | 16 | 28 |
2021 | 0 | 6 | 6 |
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Below are the most recent publications written about "Compassionate Use Trials" by people in Profiles.
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Compassionate Use of Remdesivir in Pregnant Women With Severe Coronavirus Disease 2019. Clin Infect Dis. 2021 12 06; 73(11):e3996-e4004.
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Compassionate Use of Hydroxychloroquine in Clinical Practice for Patients With Mild to Severe COVID-19 in a French University Hospital. Clin Infect Dis. 2021 12 06; 73(11):e4064-e4072.
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Compassionate use of anti-IL6 receptor antibodies in critically ill patients with acute respiratory distress syndrome due to SARS-CoV-2. Minerva Anestesiol. 2021 10; 87(10):1080-1090.
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Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report. Croat Med J. 2021 Jun 30; 62(3):288-296.
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Hydroxychloroquine Failure: The End Does Not Justify the Means. Clin Infect Dis. 2021 05 04; 72(9):e439.
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Reply to Million et al. Clin Infect Dis. 2021 05 04; 72(9):e440-e441.
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Compassionate Use of Remdesivir in Children With Severe COVID-19. Pediatrics. 2021 05; 147(5).
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[Drug use during the covid-19 pandemic in Italy.] Recenti Prog Med. 2021 05; 112(5):338-342.
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Tocilizumab improves survival in severe COVID-19 pneumonia with persistent hypoxia: a retrospective cohort study with follow-up from Mumbai, India. BMC Infect Dis. 2021 Mar 05; 21(1):241.
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Compassionate use of ruxolitinib in patients with SARS-Cov-2 infection not on mechanical ventilation: Short-term effects on inflammation and ventilation. Clin Transl Sci. 2021 05; 14(3):1062-1068.