Cleavage And Polyadenylation Specificity Factor
"Cleavage And Polyadenylation Specificity Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains four subunits of 30, 73, 100 and 160 kDa molecular size and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.
Descriptor ID |
D039223
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MeSH Number(s) |
D12.776.157.725.124.240 D12.776.664.962.444.240
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cleavage And Polyadenylation Specificity Factor".
Below are MeSH descriptors whose meaning is more specific than "Cleavage And Polyadenylation Specificity Factor".
This graph shows the total number of publications written about "Cleavage And Polyadenylation Specificity Factor" by people in this website by year, and whether "Cleavage And Polyadenylation Specificity Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 2 | 1 | 3 |
2018 | 0 | 2 | 2 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cleavage And Polyadenylation Specificity Factor" by people in Profiles.
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CFIm25 and alternative polyadenylation: Conflicting roles in cancer. Cancer Lett. 2019 09 10; 459:112-121.
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Influenza Virus NS1 Protein-RNA Interactome Reveals Intron Targeting. J Virol. 2018 12 15; 92(24).
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Interactome Analysis of NS1 Protein Encoded by Influenza A H7N9 Virus Reveals an Inhibitory Role of NS1 in Host mRNA Maturation. J Proteome Res. 2018 04 06; 17(4):1474-1484.
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Functional Evolution of Influenza Virus NS1 Protein in Currently Circulating Human 2009 Pandemic H1N1 Viruses. J Virol. 2017 09 01; 91(17).
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A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue. Nat Commun. 2017 03 06; 8:14574.
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NS1 Protein Amino Acid Changes D189N and V194I Affect Interferon Responses, Thermosensitivity, and Virulence of Circulating H3N2 Human Influenza A Viruses. J Virol. 2017 03 01; 91(5).