Hypoxia-Inducible Factor 1, alpha Subunit
"Hypoxia-Inducible Factor 1, alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted for degradation by VHL TUMOR SUPPRESSOR PROTEIN.
Descriptor ID |
D051795
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MeSH Number(s) |
D12.776.260.103.625.750 D12.776.930.125.625.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1, alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1, alpha Subunit".
This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in this website by year, and whether "Hypoxia-Inducible Factor 1, alpha Subunit" was a major or minor topic of these publications.
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click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2010 | 1 | 1 | 2 |
2012 | 2 | 1 | 3 |
2013 | 1 | 1 | 2 |
2014 | 1 | 0 | 1 |
2015 | 0 | 1 | 1 |
2016 | 1 | 1 | 2 |
2017 | 17 | 14 | 31 |
2018 | 20 | 11 | 31 |
2019 | 1 | 4 | 5 |
2020 | 1 | 0 | 1 |
2021 | 3 | 1 | 4 |
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Below are the most recent publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in Profiles.
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Increased expression of hypoxia-induced factor 1a mRNA and its related genes in myeloid blood cells from critically ill COVID-19 patients. Ann Med. 2021 12; 53(1):197-207.
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Association of rs11549465 (C1772T) variant of hypoxia-inducible factor-1a with Covid-19 susceptibility. A population-based epidemiological study. Hum Cell. 2021 Nov; 34(6):1937-1940.
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HIF-1a promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19. Signal Transduct Target Ther. 2021 08 18; 6(1):308.
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HIF-1a is a negative regulator of interferon regulatory factors: Implications for interferon production by hypoxic monocytes. Proc Natl Acad Sci U S A. 2021 06 29; 118(26).
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How could perfluorocarbon affect cytokine storm and angiogenesis in coronavirus disease 2019 (COVID-19): role of hypoxia-inducible factor 1a. Inflamm Res. 2021 Jul; 70(7):749-752.
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Hypoxia-dependent signaling in perioperative and critical care medicine. J Anesth. 2021 10; 35(5):741-756.
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Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection. Immunity. 2021 06 08; 54(6):1200-1218.e9.
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Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions. Respir Res. 2021 Apr 06; 22(1):99.
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Why does COVID-19 pathology have several clinical forms? Bioessays. 2020 12; 42(12):e2000198.
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Hypoxia, HIF-1a, and COVID-19: from pathogenic factors to potential therapeutic targets. Acta Pharmacol Sin. 2020 Dec; 41(12):1539-1546.