Transcription Factor 7-Like 2 Protein
"Transcription Factor 7-Like 2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that takes part in WNT signaling pathway. The activity of the protein is regulated via its interaction with BETA CATENIN. Transcription factor 7-like 2 protein plays an important role in the embryogenesis of the PANCREAS and ISLET CELLS.
| Descriptor ID |
D058118
|
| MeSH Number(s) |
D12.776.260.730.875 D12.776.660.235.400.800.875 D12.776.664.235.400.800.875 D12.776.930.875.875
|
| Concept/Terms |
Transcription Factor 7-Like 2 Protein- Transcription Factor 7-Like 2 Protein
- Transcription Factor 7 Like 2 Protein
- T-Cell-Specific Transcription Factor 4
- T Cell Specific Transcription Factor 4
- T Cell Transcription Factor 4
- TCF7L2 Transcription Factor
- Transcription Factor, TCF7L2
- T Cell Factor 4
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor 7-Like 2 Protein".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor 7-Like 2 Protein".
This graph shows the total number of publications written about "Transcription Factor 7-Like 2 Protein" by people in this website by year, and whether "Transcription Factor 7-Like 2 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factor 7-Like 2 Protein" by people in Profiles.
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Association of transcription factor 7-like 2 gene (TCF7L2) polymorphisms with stress-related hyperglycaemia (SRH) in intensive care and resulting outcomes: The READIAB study. Diabetes Metab. 2020 06; 46(3):243-247.
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A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer. Cancer Res. 2018 09 01; 78(17):5164-5172.
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Involvement of PUF60 in Transcriptional and Post-transcriptional Regulation of Hepatitis B Virus Pregenomic RNA Expression. Sci Rep. 2017 10 09; 7(1):12874.
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KCNJ11, ABCC8 and TCF7L2 polymorphisms and the response to sulfonylurea treatment in patients with type 2 diabetes: a bioinformatics assessment. BMC Med Genet. 2017 06 06; 18(1):64.
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Pilot cohort study on the potential role of TCF7L2 rs7903146 on ischemic heart disease among non-diabetic kidney transplant recipients. Clin Transplant. 2017 06; 31(6).
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Association of the Transcription Factor 7 Like 2 (TCF7L2) Polymorphism With Diabetic Nephropathy Risk: A Meta-Analysis. Medicine (Baltimore). 2016 Mar; 95(11):e3087.