Receptors, Purinergic P2Y12
"Receptors, Purinergic P2Y12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of purinergic P2Y receptors that have a preference for ADP binding and are coupled to GTP-BINDING PROTEIN ALPHA SUBUNIT, GI. The P2Y12 purinergic receptors are found in PLATELETS where they play an important role regulating PLATELET ACTIVATION.
| Descriptor ID |
D058925
|
| MeSH Number(s) |
D12.776.543.750.695.700.720.500.300 D12.776.543.750.720.700.720.750.300
|
| Concept/Terms |
Receptors, Purinergic P2Y12- Receptors, Purinergic P2Y12
- P2Y12 Receptors, Purinergic
- Purinergic P2Y12 Receptors
- Purinergic Receptor P2Y, G-Protein Coupled, 12
- Purinoceptor P2Y12
- P2Y12, Purinoceptor
- P2Y12 Purinoceptors
- Purinoceptors, P2Y12
- P2Y(ADP) Receptor
- P2Y(T) Receptor
- P2Y12 Purinoceptor
- Purinoceptor, P2Y12
- Purinoceptor P2T
- P2T, Purinoceptor
- Purinergic Receptor P2Y12
- P2Y12, Purinergic Receptor
- P2T Purinoceptor
- Purinoceptor, P2T
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2Y12".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
- Receptors, Purinergic P2Y [D12.776.543.750.695.700.720.500]
- Receptors, Purinergic P2Y12 [D12.776.543.750.695.700.720.500.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2Y [D12.776.543.750.720.700.720.750]
- Receptors, Purinergic P2Y12 [D12.776.543.750.720.700.720.750.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2Y12".
This graph shows the total number of publications written about "Receptors, Purinergic P2Y12" by people in this website by year, and whether "Receptors, Purinergic P2Y12" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 2 | 9 | 11 |
| 2018 | 4 | 3 | 7 |
| 2019 | 1 | 4 | 5 |
| 2020 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Purinergic P2Y12" by people in Profiles.
-
Advances in the Pharmacogenomics of Antiplatelet Therapy. Am J Ther. 2020 Sep/Oct; 27(5):e477-e484.
-
Severe bleeding and absent ADP-induced platelet aggregation associated with inherited combined CalDAG-GEFI and P2Y12 deficiencies. Haematologica. 2020 07; 105(7):e361-e364.
-
Updated Expert Consensus Statement on Platelet Function and Genetic Testing for Guiding P2Y12 Receptor Inhibitor Treatment in Percutaneous Coronary Intervention. JACC Cardiovasc Interv. 2019 08 26; 12(16):1521-1537.
-
Role of Platelet Size Revisited-Function and Protein Composition of Large and Small Platelets. Thromb Haemost. 2019 Mar; 119(3):407-420.
-
Diurnal Variability of On-Treatment Platelet Reactivity in Clopidogrel versus Prasugrel Treated Acute Coronary Syndrome Patients: A Pre-Specified TROPICAL-ACS Sub-Study. Thromb Haemost. 2019 Apr; 119(4):660-667.
-
Evaluation of platelet activity by multiple electrode impedance aggregometry in acute coronary syndromes: pilot study in a Brazilian tertiary-care public hospital. Braz J Med Biol Res. 2019 Jan 10; 52(2):e8001.
-
Oral Antiplatelet Therapy for Secondary Prevention of Acute Coronary Syndrome. Am J Cardiovasc Drugs. 2018 Dec; 18(6):457-472.
-
Is There a Role for Preoperative Platelet Function Testing in Patients Undergoing Cardiac Surgery During Antiplatelet Therapy? Circulation. 2018 11 06; 138(19):2145-2159.
-
Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites. Clin Pharmacokinet. 2018 10; 57(10):1347-1354.
-
Pleiotropic effects of antiplatelet treatment in patients with coronary artery disease. Hellenic J Cardiol. 2018 Nov - Dec; 59(6):344-346.