"Iron Overload" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
| Descriptor ID |
D019190
|
| MeSH Number(s) |
C18.452.565.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Iron Overload".
Below are MeSH descriptors whose meaning is more specific than "Iron Overload".
This graph shows the total number of publications written about "Iron Overload" by people in this website by year, and whether "Iron Overload" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2017 | 14 | 2 | 16 |
| 2018 | 16 | 4 | 20 |
| 2019 | 5 | 2 | 7 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Iron Overload" by people in Profiles.
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SARS-CoV-2 infection in patients with ß-thalassemia: The French experience. Transfus Clin Biol. 2022 Feb; 29(1):70-74.
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Deferoxamine B: A Natural, Excellent and Versatile Metal Chelator. Molecules. 2021 May 28; 26(11).
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SARS-CoV-2 infection in patients with ß-thalassemia: Experience from Lebanon. Am J Hematol. 2021 08 01; 96(8):E285-E288.
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A case of ischemic colitis in a patient with non transfusion dependent thalassemia (NTDT) infected by SARS-COV-2. Pediatr Hematol Oncol. 2021 11; 38(8):753-756.
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Hepatic Failure in COVID-19: Is Iron Overload the Dangerous Trigger? Cells. 2021 05 04; 10(5).
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The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators. Biomed Pharmacother. 2021 Apr; 136:111228.
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Hepcidin is a friend rather than a foe in COVID19-induced complications. Acta Biomed. 2020 11 05; 91(4):e2020138.
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Iron overload and Hepcidin overexpression could play a key role in COVID infection, and may explain vulnerability in elderly, diabetics, and obese patients. Acta Biomed. 2020 09 07; 91(3):e2020013.
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COVID-19 as part of the hyperferritinemic syndromes: the role of iron depletion therapy. Immunol Res. 2020 08; 68(4):213-224.
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Can iron chelation as an adjunct treatment of COVID-19 improve the clinical outcome? Eur J Clin Pharmacol. 2020 Nov; 76(11):1619-1620.