Macromolecular Substances
"Macromolecular Substances" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.
| Descriptor ID |
D046911
|
| MeSH Number(s) |
D05
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Macromolecular Substances".
Below are MeSH descriptors whose meaning is more specific than "Macromolecular Substances".
This graph shows the total number of publications written about "Macromolecular Substances" by people in this website by year, and whether "Macromolecular Substances" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2017 | 5 | 4 | 9 |
| 2018 | 3 | 2 | 5 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Macromolecular Substances" by people in Profiles.
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Supramolecular Cylinders Target Bulge Structures in the 5' UTR of the RNA Genome of SARS-CoV-2 and Inhibit Viral Replication*. Angew Chem Int Ed Engl. 2021 08 09; 60(33):18144-18151.
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Assessment of protein-protein interfaces in cryo-EM derived assemblies. Nat Commun. 2021 06 07; 12(1):3399.
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Expanding capabilities and infrastructure for cryo-EM. Nat Methods. 2021 05; 18(5):437-438.
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Strategies for Optimization of Cryogenic Electron Tomography Data Acquisition. J Vis Exp. 2021 03 19; (169).
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RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences. Nucleic Acids Res. 2021 01 08; 49(D1):D437-D451.
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Editorial overview: Macromolecular assemblies. Curr Opin Struct Biol. 2019 04; 55:iii-v.
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First evidence of formation of pre-molten globule state in myoglobin: A macromolecular crowding approach towards protein folding in vivo. Int J Biol Macromol. 2019 Apr 01; 126:1288-1294.
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Intrinsically disordered proteins in crowded milieu: when chaos prevails within the cellular gumbo. Cell Mol Life Sci. 2018 Nov; 75(21):3907-3929.
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Supramolecular Reassembly of Self-Exfoliated Ionic Covalent Organic Nanosheets for Label-Free Detection of Double-Stranded DNA. Angew Chem Int Ed Engl. 2018 07 09; 57(28):8443-8447.
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CCP4i2: the new graphical user interface to the CCP4 program suite. Acta Crystallogr D Struct Biol. 2018 02 01; 74(Pt 2):68-84.