Growth Differentiation Factor 1
"Growth Differentiation Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.
| Descriptor ID |
D055452
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| MeSH Number(s) |
D12.644.276.954.300.100 D12.644.276.954.550.100 D12.776.467.942.300.100 D12.776.467.942.550.100 D23.529.942.300.100 D23.529.942.550.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Growth Differentiation Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Growth Differentiation Factor 1".
This graph shows the total number of publications written about "Growth Differentiation Factor 1" by people in this website by year, and whether "Growth Differentiation Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Growth Differentiation Factor 1" by people in Profiles.
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Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands. Nat Genet. 2017 Nov; 49(11):1593-1601.