Kwok-Hung Chan

Institutionthe University of Hong Kong
AddressHong Kong
China
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 41 Covid-19 publications, with a maximum of 5 publications in June 2020 and July 2020 and December 2020
    All Publications
    Bar chart showing 364 publications over 27 distinct years, with a maximum of 30 publications in 2013 and 2020
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. To KK, Hung IF, Ip JD, Chu AW, Chan WM, Tam AR, Fong CH, Yuan S, Tsoi HW, Ng AC, Lee LL, Wan P, Tso EY, To WK, Tsang DN, Chan KH, Huang JD, Kok KH, Cheng VC, Yuen KY. Coronavirus Disease 2019 (COVID-19) Re-infection by a Phylogenetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Strain Confirmed by Whole Genome Sequencing. Clin Infect Dis. 2021 11 02; 73(9):e2946-e2951. PMID: 32840608.
      Citations: 275     Fields:    Translation:Humans
    2. Lu L, Chu AW, Zhang RR, Chan WM, Ip JD, Tsoi HW, Chen LL, Cai JP, Lung DC, Tam AR, Yau YS, Kwan MY, To WK, Tsang OT, Lee LL, Yi H, Ip TC, Poon RW, Siu GK, Mok BW, Cheng VC, Chan KH, Yuen KY, Hung IF, To KK. The impact of spike N501Y mutation on neutralizing activity and RBD binding of SARS-CoV-2 convalescent serum. EBioMedicine. 2021 Sep; 71:103544. PMID: 34419925.
      Citations: 4     Fields:    Translation:Humans
    3. Li C, Chen YX, Liu FF, Lee AC, Zhao Y, Ye ZH, Cai JP, Chu H, Zhang RQ, Chan KH, Chiu KH, Lung DC, Sridhar S, Hung IF, To KK, Zhang AJ, Chan JF, Yuen KY. Absence of Vaccine-enhanced Disease With Unexpected Positive Protection Against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by Inactivated Vaccine Given Within 3 Days of Virus Challenge in Syrian Hamster Model. Clin Infect Dis. 2021 08 02; 73(3):e719-e734. PMID: 33515458.
      Citations: 4     Fields:    Translation:HumansAnimals
    4. Chen LL, Lu L, Choi CY, Cai JP, Tsoi HW, Chu AW, Ip JD, Chan WM, Zhang RR, Zhang X, Tam AR, Lau DP, To WK, Que TL, Yip CC, Chan KH, Cheng VC, Yuen KY, Hung IF, To KK. Impact of SARS-CoV-2 variant-associated RBD mutations on the susceptibility to serum antibodies elicited by COVID-19 infection or vaccination. Clin Infect Dis. 2021 Jul 26. PMID: 34309648.
      Citations: 10     Fields:    
    5. To KK, Chan WM, Ip JD, Chu AW, Tam AR, Liu R, Wu AK, Lung KC, Tsang OT, Lau DP, To WK, Kwan MY, Yau YS, Ng AC, Yip CC, Chan KH, Tse H, Hung IF, Yuen KY. Unique Clusters of Severe Acute Respiratory Syndrome Coronavirus 2 Causing a Large Coronavirus Disease 2019 Outbreak in Hong Kong. Clin Infect Dis. 2021 07 01; 73(1):137-142. PMID: 32756996.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    6. Yip CCY, Leung KH, Ng ACK, Chan KH, To KKW, Chan JFW, Hung IFN, Cheng VCC, Sridhar S. Comparative evaluation of a dual-target real-time RT-PCR assay for COVID-19 diagnosis and assessment of performance in pooled saliva and nasopharyngeal swab samples. Expert Rev Mol Diagn. 2021 07; 21(7):741-747. PMID: 34014785.
      Citations:    Fields:    Translation:Humans
    7. Chung TW, Zhang H, Wong FK, Sridhar S, Chan KH, Cheng VC, Yuen KY, Hung IF, Mak HK. Neurosensory Rehabilitation and Olfactory Network Recovery in Covid-19-related Olfactory Dysfunction. Brain Sci. 2021 May 23; 11(6). PMID: 34071007.
      Citations: 1     
    8. To KK, Hung IF, Chan KH, Yuan S, To WK, Tsang DN, Cheng VC, Chen Z, Kok KH, Yuen KY. Serum Antibody Profile of a Patient With Coronavirus Disease 2019 Reinfection. Clin Infect Dis. 2021 05 18; 72(10):e659-e662. PMID: 32966566.
      Citations: 23     Fields:    Translation:Humans
    9. Wang P, Lau SY, Deng S, Chen P, Mok BW, Zhang AJ, Lee AC, Chan KH, Tam RC, Xu H, Zhou R, Song W, Liu L, To KK, Chan JF, Chen Z, Yuen KY, Chen H. Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein. Nat Commun. 2021 05 13; 12(1):2790. PMID: 33986286.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    10. Chan WM, Ip JD, Chu AW, Tse H, Tam AR, Li X, Kwan MY, Yau YS, Leung WS, Chik TS, To WK, Ng AC, Yip CC, Poon RW, Chan KH, Wong SC, Choi GK, Lung DC, Cheng VC, Hung IF, Yuen KY, To KK. Phylogenomic analysis of COVID-19 summer and winter outbreaks in Hong Kong: An observational study. Lancet Reg Health West Pac. 2021 May; 10:100130. PMID: 33778795.
      Citations: 4     
    11. Yeung ML, Teng JLL, Jia L, Zhang C, Huang C, Cai JP, Zhou R, Chan KH, Zhao H, Zhu L, Siu KL, Fung SY, Yung S, Chan TM, To KK, Chan JF, Cai Z, Lau SKP, Chen Z, Jin DY, Woo PCY, Yuen KY. Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. Cell. 2021 04 15; 184(8):2212-2228.e12. PMID: 33713620.
      Citations: 28     Fields:    Translation:HumansCells
    12. Lu L, Fong CH, Zhang AJ, Wu WL, Li IC, Lee AC, Dissanayake TK, Chen L, Hung IF, Chan KH, Chu H, Kok KH, Yuen KY, To KK. Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine. Vaccines (Basel). 2020 Dec 11; 8(4). PMID: 33322574.
      Citations: 2     
    13. Chan JF, Zhang AJ, Yuan S, Poon VK, Chan CC, Lee AC, Chan WM, Fan Z, Tsoi HW, Wen L, Liang R, Cao J, Chen Y, Tang K, Luo C, Cai JP, Kok KH, Chu H, Chan KH, Sridhar S, Chen Z, Chen H, To KK, Yuen KY. Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility. Clin Infect Dis. 2020 12 03; 71(9):2428-2446. PMID: 32215622.
      Citations: 358     Fields:    Translation:Animals
    14. Lau SY, Wang P, Mok BW, Zhang AJ, Chu H, Lee AC, Deng S, Chen P, Chan KH, Song W, Chen Z, To KK, Chan JF, Yuen KY, Chen H. Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction. Emerg Microbes Infect. 2020 Dec; 9(1):837-842. PMID: 32301390.
      Citations: 103     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    15. Chen JH, Yip CC, Poon RW, Chan KH, Cheng VC, Hung IF, Chan JF, Yuen KY, To KK. Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay for the detection of SARS-CoV-2. Emerg Microbes Infect. 2020 Dec; 9(1):1356-1359. PMID: 32459137.
      Citations: 47     Fields:    Translation:HumansCellsPHPublic Health
    16. Liu L, To KK, Chan KH, Wong YC, Zhou R, Kwan KY, Fong CH, Chen LL, Choi CY, Lu L, Tsang OT, Leung WS, To WK, Hung IF, Yuen KY, Chen Z. High neutralizing antibody titer in intensive care unit patients with COVID-19. Emerg Microbes Infect. 2020 Dec; 9(1):1664-1670. PMID: 32618497.
      Citations: 49     Fields:    Translation:HumansCellsPHPublic Health
    17. Chan JF, Yuan S, Zhang AJ, Poon VK, Chan CC, Lee AC, Fan Z, Li C, Liang R, Cao J, Tang K, Luo C, Cheng VC, Cai JP, Chu H, Chan KH, To KK, Sridhar S, Yuen KY. Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2020 11 19; 71(16):2139-2149. PMID: 32472679.
      Citations: 77     Fields:    Translation:AnimalsCellsPHPublic Health
    18. Ip JD, Kok KH, Chan WM, Chu AW, Wu WL, Yip CC, To WK, Tsang OT, Leung WS, Chik TS, Chan KH, Hung IF, Yuen KY, To KK. Intra-host non-synonymous diversity at a neutralizing antibody epitope of SARS-CoV-2 spike protein N-terminal domain. Clin Microbiol Infect. 2021 Sep; 27(9):1350.e1-1350.e5. PMID: 33144203.
      Citations: 7     Fields:    Translation:Humans
    19. Wong CK, Luk HK, Lai WH, Lau YM, Zhang RR, Wong AC, Lo GC, Chan KH, Hung IF, Tse HF, Woo PC, Lau SK, Siu CW. Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Platform to Study SARS-CoV-2 Related Myocardial Injury. Circ J. 2020 10 23; 84(11):2027-2031. PMID: 32981925.
      Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
    20. Li X, Chan JF, Li KK, Tso EY, Yip CC, Sridhar S, Chung TW, Chiu KH, Hung DL, Wu AK, Chau SK, Liu R, Lung KC, Tam AR, Cheng VC, To KK, Chan KH, Hung IF, Yuen KY. Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms. Infection. 2021 Apr; 49(2):257-265. PMID: 32944840.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    21. Fong CH, Cai JP, Dissanayake TK, Chen LL, Choi CY, Wong LH, Ng AC, Pang PKP, Ho DT, Poon RW, Chung TW, Sridhar S, Chan KH, Chan JF, Hung IF, Yuen KY, To KK. Improved Detection of Antibodies against SARS-CoV-2 by Microsphere-Based Antibody Assay. Int J Mol Sci. 2020 Sep 09; 21(18). PMID: 32916926.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    22. Yip CC, Sridhar S, Leung KH, Ng AC, Chan KH, Chan JF, Tsang OT, Hung IF, Cheng VC, Yuen KY, To KK. Development and Evaluation of Novel and Highly Sensitive Single-Tube Nested Real-Time RT-PCR Assays for SARS-CoV-2 Detection. Int J Mol Sci. 2020 Aug 07; 21(16). PMID: 32784770.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    23. To KK, Tsang OT, Yip CC, Chan KH, Wu TC, Chan JM, Leung WS, Chik TS, Choi CY, Kandamby DH, Lung DC, Tam AR, Poon RW, Fung AY, Hung IF, Cheng VC, Chan JF, Yuen KY. Consistent Detection of 2019 Novel Coronavirus in Saliva. Clin Infect Dis. 2020 07 28; 71(15):841-843. PMID: 32047895.
      Citations: 548     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    24. Chen JH, Yip CC, Chan JF, Poon RW, To KK, Chan KH, Cheng VC, Yuen KY. Clinical Performance of the Luminex NxTAG CoV Extended Panel for SARS-CoV-2 Detection in Nasopharyngeal Specimens from COVID-19 Patients in Hong Kong. J Clin Microbiol. 2020 Jul 23; 58(8). PMID: 32482633.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    25. To KK, Chua GT, Kwok KL, Wong JS, Au DCY, Lam YY, Wong WH, Ho MH, Chan GC, Chui CS, Li X, Tung KT, Wong RS, Tso WW, Wong IC, Wong CS, Fong CH, Chan KH, Yuen KY, Ip P, Kwan MY. False-positive SARS-CoV-2 serology in 3 children with Kawasaki disease. Diagn Microbiol Infect Dis. 2020 Nov; 98(3):115141. PMID: 32795776.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    26. Chan KH, Sridhar S, Zhang RR, Chu H, Chu H, Fung AY, Chan G, Chan JF, Chan JF, To KK, To KK, Hung IF, Cheng VC, Cheng VC, Yuen KY. Factors affecting stability and infectivity of SARS-CoV-2. J Hosp Infect. 2020 Oct; 106(2):226-231. PMID: 32652214.
      Citations: 62     Fields:    Translation:HumansCellsPHPublic Health
    27. Zhang BZ, Hu YF, Chen LL, Yau T, Tong YG, Hu JC, Cai JP, Chan KH, Dou Y, Deng J, Wang XL, Hung IF, To KK, Yuen KY, Huang JD. Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients. Cell Res. 2020 08; 30(8):702-704. PMID: 32612199.
      Citations: 34     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    28. Chan WM, Ip JD, Chu AW, Yip CC, Lo LS, Chan KH, Ng AC, Poon RW, To WK, Tsang OT, Leung WS, Kwan MY, Chua GT, Chung TW, Hung IF, Kok KH, Cheng VC, Chan JF, Yuen KY, To KK. Identification of nsp1 gene as the target of SARS-CoV-2 real-time RT-PCR using nanopore whole-genome sequencing. J Med Virol. 2020 11; 92(11):2725-2734. PMID: 32501535.
      Citations: 12     Fields:    Translation:Humans
    29. Hung IF, Cheng VC, Li X, Tam AR, Hung DL, Chiu KH, Yip CC, Cai JP, Ho DT, Wong SC, Leung SS, Chu MY, Tang MO, Chen JH, Poon RW, Fung AY, Zhang RR, Yan EY, Chen LL, Choi CY, Leung KH, Chung TW, Lam SH, Lam TP, Chan JF, Chan KH, Wu TC, Ho PL, Chan JW, Lau CS, To KK, Yuen KY. SARS-CoV-2 shedding and seroconversion among passengers quarantined after disembarking a cruise ship: a case series. Lancet Infect Dis. 2020 09; 20(9):1051-1060. PMID: 32539986.
      Citations: 42     Fields:    Translation:HumansCellsPHPublic Health
    30. Cheng VC, Wong SC, Chan VW, So SY, Chen JH, Yip CC, Chan KH, Chu H, Chung TW, Sridhar S, To KK, Chan JF, Hung IF, Ho PL, Yuen KY. Air and environmental sampling for SARS-CoV-2 around hospitalized patients with coronavirus disease 2019 (COVID-19). Infect Control Hosp Epidemiol. 2020 11; 41(11):1258-1265. PMID: 32507114.
      Citations: 45     Fields:    Translation:HumansCellsPHPublic Health
    31. Chung TW, Sridhar S, Zhang AJ, Chan KH, Li HL, Wong FK, Ng MY, Tsang RK, Lee AC, Fan Z, Ho RS, Luk SY, Kan WK, Lam SH, Wu AK, Leung SM, Chan WM, Ng PY, To KK, Cheng VC, Lung KC, Hung IF, Yuen KY. Olfactory Dysfunction in Coronavirus Disease 2019 Patients: Observational Cohort Study and Systematic Review. Open Forum Infect Dis. 2020 Jun; 7(6):ofaa199. PMID: 32548209.
      Citations: 31     
    32. To KK, Cheng VC, Cai JP, Chan KH, Chen LL, Wong LH, Choi CY, Fong CH, Ng AC, Lu L, Luo CT, Situ J, Chung TW, Wong SC, Kwan GS, Sridhar S, Chan JF, Fan CY, Chuang VWM, Kok KH, Hung IF, Yuen KY. Seroprevalence of SARS-CoV-2 in Hong Kong and in residents evacuated from Hubei province, China: a multicohort study. Lancet Microbe. 2020 Jul; 1(3):e111-e118. PMID: 33230504.
      Citations: 23     
    33. Yip CC, Sridhar S, Cheng AK, Leung KH, Choi GK, Chen JH, Poon RW, Chan KH, Wu AK, Chan HS, Chau SK, Chung TW, To KK, Tsang OT, Hung IF, Cheng VC, Yuen KY, Chan JF. Evaluation of the commercially available LightMix® Modular E-gene kit using clinical and proficiency testing specimens for SARS-CoV-2 detection. J Clin Virol. 2020 08; 129:104476. PMID: 32516739.
      Citations: 18     Fields:    Translation:HumansCellsPHPublic Health
    34. Zhou J, Li C, Liu X, Chiu MC, Zhao X, Wang D, Wei Y, Lee A, Lee A, Zhang AJ, Chu H, Cai JP, Yip CC, Chan IH, Wong KK, Tsang OT, Chan KH, Chan JF, To KK, Chen H, Yuen KY. Infection of bat and human intestinal organoids by SARS-CoV-2. Nat Med. 2020 07; 26(7):1077-1083. PMID: 32405028.
      Citations: 168     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    35. Hung IF, Lung KC, Tso EY, Liu R, Chung TW, Chu MY, Ng YY, Lo J, Chan J, Tam AR, Shum HP, Chan V, Wu AK, Sin KM, Leung WS, Law WL, Lung DC, Sin S, Yeung P, Yip CC, Zhang RR, Fung AY, Yan EY, Leung KH, Ip JD, Chu AW, Chan WM, Ng AC, Lee R, Fung K, Yeung A, Wu TC, Chan JW, Yan WW, Chan WM, Chan JF, Lie AK, Tsang OT, Cheng VC, Que TL, Lau CS, Chan KH, To KK, Yuen KY. Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial. Lancet. 2020 05 30; 395(10238):1695-1704. PMID: 32401715.
      Citations: 559     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    36. Chan JF, Yip CC, To KK, Tang TH, Wong SC, Leung KH, Fung AY, Ng AC, Zou Z, Tsoi HW, Choi GK, Tam AR, Cheng VC, Chan KH, Tsang OT, Yuen KY. Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens. J Clin Microbiol. 2020 04 23; 58(5). PMID: 32132196.
      Citations: 320     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    37. Chu H, Chan JF, Yuen TT, Shuai H, Yuan S, Wang Y, Hu B, Yip CC, Tsang JO, Huang X, Chai Y, Yang D, Hou Y, Chik KK, Zhang X, Fung AY, Tsoi HW, Cai JP, Chan WM, Ip JD, Chu AW, Zhou J, Lung DC, Kok KH, To KK, Tsang OT, Chan KH, Yuen KY. Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study. Lancet Microbe. 2020 May; 1(1):e14-e23. PMID: 32835326.
      Citations: 232     
    38. Yip CC, Ho CC, Chan JF, To KK, Chan HS, Wong SC, Leung KH, Fung AY, Ng AC, Zou Z, Tam AR, Chung TW, Chan KH, Hung IF, Cheng VC, Tsang OT, Tsui SKW, Yuen KY. Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical Specimens. Int J Mol Sci. 2020 Apr 08; 21(7). PMID: 32276333.
      Citations: 29     Fields:    Translation:HumansCellsPHPublic Health
    39. Leung NHL, Chu DKW, Shiu EYC, Chan KH, McDevitt JJ, Hau BJP, Yen HL, Li Y, Ip DKM, Peiris JSM, Seto WH, Leung GM, Milton DK, Cowling BJ. Respiratory virus shedding in exhaled breath and efficacy of face masks. Nat Med. 2020 05; 26(5):676-680. PMID: 32371934.
      Citations: 563     Fields:    Translation:HumansCellsPHPublic Health
    40. To KK, Tsang OT, Leung WS, Tam AR, Wu TC, Lung DC, Yip CC, Cai JP, Chan JM, Chik TS, Lau DP, Choi CY, Chen LL, Chan WM, Chan KH, Ip JD, Ng AC, Poon RW, Luo CT, Cheng VC, Chan JF, Hung IF, Chen Z, Chen H, Yuen KY. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020 05; 20(5):565-574. PMID: 32213337.
      Citations: 1183     Fields:    Translation:HumansCellsPHPublic Health
    41. Chan JF, Yuan S, Kok KH, To KK, Chu H, Yang J, Xing F, Liu J, Yip CC, Poon RW, Tsoi HW, Lo SK, Chan KH, Poon VK, Chan WM, Ip JD, Cai JP, Cheng VC, Chen H, Hui CK, Yuen KY. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020 02 15; 395(10223):514-523. PMID: 31986261.
      Citations: 2937     Fields:    Translation:HumansCells
    42. To KKW, Chan KH, Ho J, Pang PKP, Ho DTY, Chang ACH, Seng CW, Yip CCY, Cheng VCC, Hung IFN, Yuen KY. Respiratory virus infection among hospitalized adult patients with or without clinically apparent respiratory infection: a prospective cohort study. Clin Microbiol Infect. 2019 Dec; 25(12):1539-1545. PMID: 31004768.
      Citations: 13     Fields:    Translation:HumansCells
    43. Liu L, Wei Q, Lin Q, Fang J, Wang H, Kwok H, Tang H, Nishiura K, Peng J, Tan Z, Wu T, Cheung KW, Chan KH, Alvarez X, Qin C, Lackner A, Perlman S, Yuen KY, Chen Z. Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection. JCI Insight. 2019 02 21; 4(4). PMID: 30830861.
      Citations: 343     Fields:    Translation:HumansAnimalsCells
    44. Lau SKP, Fan RYY, Luk HKH, Zhu L, Fung J, Li KSM, Wong EYM, Ahmed SS, Chan JFW, Kok RKH, Chan KH, Wernery U, Yuen KY, Woo PCY. Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins. Emerg Microbes Infect. 2018 Dec 10; 7(1):209. PMID: 30531999.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    45. Cowling BJ, Chan KH, Peiris JS. Influenza-like illness and viral aetiology in Hong Kong children. Hong Kong Med J. 2018 Oct; 24 Suppl 6(5):12-15. PMID: 30229729.
      Citations: 1     Fields:    Translation:HumansCells
    46. Woo PCY, Lau SKP, Chen Y, Wong EYM, Chan KH, Chen H, Zhang L, Xia N, Yuen KY. Rapid detection of MERS coronavirus-like viruses in bats: pote1ntial for tracking MERS coronavirus transmission and animal origin. Emerg Microbes Infect. 2018 Mar 07; 7(1):18. PMID: 29511173.
      Citations: 9     Fields:    Translation:AnimalsCells
    47. To KK, Lu L, Yip CC, Poon RW, Fung AM, Cheng A, Lui DH, Ho DT, Hung IF, Chan KH, Yuen KY. Additional molecular testing of saliva specimens improves the detection of respiratory viruses. Emerg Microbes Infect. 2017 Jun 07; 6(6):e49. PMID: 28588283.
      Citations: 40     Fields:    Translation:HumansCells
    48. Cheung NN, Lai KK, Dai J, Kok KH, Chen H, Chan KH, Yuen KY, Kao RYT. Broad-spectrum inhibition of common respiratory RNA viruses by a pyrimidine synthesis inhibitor with involvement of the host antiviral response. J Gen Virol. 2017 May; 98(5):946-954. PMID: 28555543.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    49. Lau SK, Wernery R, Wong EY, Joseph S, Tsang AK, Patteril NA, Elizabeth SK, Chan KH, Muhammed R, Kinne J, Yuen KY, Wernery U, Woo PC. Polyphyletic origin of MERS coronaviruses and isolation of a novel clade A strain from dromedary camels in the United Arab Emirates. Emerg Microbes Infect. 2016 Dec 21; 5(12):e128. PMID: 27999424.
      Citations: 18     Fields:    Translation:AnimalsCells
    50. Lau SK, Chan JF, Hung IF, Cheng VC, Sridhar S, Yip CC, Chan KH, Woo PC. Middle East Respiratory Syndrome Interpreted: Human Herpesvirus 6B Pneumonia. Am J Med. 2016 09; 129(9):945-7. PMID: 27215907.
      Citations:    Fields:    Translation:HumansCells
    51. Chen Y, Chan KH, Hong C, Kang Y, Ge S, Chen H, Wong EY, Joseph S, Patteril NG, Wernery U, Xia N, Lau SK, Woo PC. A highly specific rapid antigen detection assay for on-site diagnosis of MERS. J Infect. 2016 07; 73(1):82-4. PMID: 27144915.
      Citations: 20     Fields:    Translation:HumansCells
    52. Yip CC, Lam CS, Luk HK, Wong EY, Lee RA, So LY, Chan KH, Cheng VC, Yuen KY, Woo PC, Lau SK. A six-year descriptive epidemiological study of human coronavirus infections in hospitalized patients in Hong Kong. Virol Sin. 2016 Feb; 31(1):41-8. PMID: 26920709.
      Citations: 13     Fields:    Translation:HumansCells
    53. Yeung ML, Yao Y, Jia L, Chan JF, Chan KH, Cheung KF, Chen H, Poon VK, Tsang AK, To KK, Yiu MK, Teng JL, Chu H, Zhou J, Zhang Q, Deng W, Lau SK, Lau JY, Woo PC, Chan TM, Yung S, Zheng BJ, Jin DY, Mathieson PW, Qin C, Yuen KY. MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2. Nat Microbiol. 2016 Feb 22; 1:16004. PMID: 27572168.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    54. Chan JF, Choi GK, Tsang AK, Tee KM, Lam HY, Yip CC, To KK, Cheng VC, Yeung ML, Lau SK, Woo PC, Chan KH, Tang BS, Yuen KY. Development and Evaluation of Novel Real-Time Reverse Transcription-PCR Assays with Locked Nucleic Acid Probes Targeting Leader Sequences of Human-Pathogenic Coronaviruses. J Clin Microbiol. 2015 Aug; 53(8):2722-6. PMID: 26019210.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    55. Chen Y, Chan KH, Kang Y, Chen H, Luk HK, Poon RW, Chan JF, Yuen KY, Xia N, Lau SK, Woo PC. A sensitive and specific antigen detection assay for Middle East respiratory syndrome coronavirus. Emerg Microbes Infect. 2015 Apr; 4(4):e26. PMID: 26421268.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    56. Lau SK, Woo PC, Li KS, Tsang AK, Fan RY, Luk HK, Cai JP, Chan KH, Zheng BJ, Wang M, Yuen KY. Discovery of a novel coronavirus, China Rattus coronavirus HKU24, from Norway rats supports the murine origin of Betacoronavirus 1 and has implications for the ancestor of Betacoronavirus lineage A. J Virol. 2015 Mar; 89(6):3076-92. PMID: 25552712.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    57. Woo PC, Lau SK, Wernery U, Wong EY, Tsang AK, Johnson B, Yip CC, Lau CC, Sivakumar S, Cai JP, Fan RY, Chan KH, Mareena R, Yuen KY. Novel betacoronavirus in dromedaries of the Middle East, 2013. Emerg Infect Dis. 2014 Apr; 20(4):560-72. PMID: 24655427.
      Citations: 50     Fields:    Translation:AnimalsCells
    58. Chu H, Zhou J, Wong BH, Li C, Cheng ZS, Lin X, Poon VK, Sun T, Lau CC, Chan JF, To KK, Chan KH, Lu L, Zheng BJ, Yuen KY. Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response. Virology. 2014 Apr; 454-455:197-205. PMID: 24725946.
      Citations: 85     Fields:    Translation:HumansCells
    59. Lu L, Liu Q, Zhu Y, Chan KH, Qin L, Li Y, Wang Q, Chan JF, Du L, Yu F, Ma C, Ye S, Yuen KY, Zhang R, Jiang S. Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor. Nat Commun. 2014; 5:3067. PMID: 24473083.
      Citations: 157     Fields:    Translation:HumansCells
    60. Chan JF, Chan KH, Kao RY, To KK, Zheng BJ, Li CP, Li PT, Dai J, Mok FK, Chen H, Hayden FG, Yuen KY. Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus. J Infect. 2013 Dec; 67(6):606-16. PMID: 24096239.
      Citations: 159     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    61. Lau SKP, Lau CCY, Chan KH, Li CPY, Chen H, Jin DY, Chan JFW, Woo PCY, Yuen KY. Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment. J Gen Virol. 2013 Dec; 94(Pt 12):2679-2690. PMID: 24077366.
      Citations: 172     Fields:    Translation:HumansCells
    62. Zhou J, Chu H, Li C, Wong BH, Cheng ZS, Poon VK, Sun T, Lau CC, Wong KK, Chan JY, Chan JF, To KK, Chan KH, Zheng BJ, Yuen KY. Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis. J Infect Dis. 2014 May 01; 209(9):1331-42. PMID: 24065148.
      Citations: 180     Fields:    Translation:HumansAnimalsCells
    63. Chan JF, Chan KH, Yuen KY. Reply to Leow. J Infect Dis. 2013 Oct 15; 208(8):1351-2. PMID: 23878323.
      Citations:    Fields:    Translation:HumansCells
    64. Lau SK, Li KS, Tsang AK, Lam CS, Ahmed S, Chen H, Chan KH, Woo PC, Yuen KY. Genetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: implications for the origin of the novel Middle East respiratory syndrome coronavirus. J Virol. 2013 Aug; 87(15):8638-50. PMID: 23720729.
      Citations: 125     Fields:    Translation:AnimalsCells
    65. Chan KH, Chan JF, Tse H, Chen H, Lau CC, Cai JP, Tsang AK, Xiao X, To KK, Lau SK, Woo PC, Zheng BJ, Wang M, Yuen KY. Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests. J Infect. 2013 Aug; 67(2):130-40. PMID: 23583636.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    66. Chan JF, Chan KH, Choi GK, To KK, Tse H, Cai JP, Yeung ML, Cheng VC, Chen H, Che XY, Lau SK, Woo PC, Yuen KY. Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation. J Infect Dis. 2013 Jun 01; 207(11):1743-52. PMID: 23532101.
      Citations: 127     Fields:    Translation:HumansCells
    67. Lau SK, Li KS, Tsang AK, Shek CT, Wang M, Choi GK, Guo R, Wong BH, Poon RW, Lam CS, Wang SY, Fan RY, Chan KH, Zheng BJ, Woo PC, Yuen KY. Recent transmission of a novel alphacoronavirus, bat coronavirus HKU10, from Leschenault's rousettes to pomona leaf-nosed bats: first evidence of interspecies transmission of coronavirus between bats of different suborders. J Virol. 2012 Nov; 86(21):11906-18. PMID: 22933277.
      Citations: 46     Fields:    Translation:AnimalsCells
    68. Lau SK, Woo PC, Yip CC, Fan RY, Huang Y, Wang M, Guo R, Lam CS, Tsang AK, Lai KK, Chan KH, Che XY, Zheng BJ, Yuen KY. Isolation and characterization of a novel Betacoronavirus subgroup A coronavirus, rabbit coronavirus HKU14, from domestic rabbits. J Virol. 2012 May; 86(10):5481-96. PMID: 22398294.
      Citations: 72     Fields:    Translation:AnimalsCells
    69. Woo PC, Lau SK, Lam CS, Lau CC, Tsang AK, Lau JH, Bai R, Teng JL, Tsang CC, Wang M, Zheng BJ, Chan KH, Yuen KY. Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus. J Virol. 2012 Apr; 86(7):3995-4008. PMID: 22278237.
      Citations: 529     Fields:    Translation:HumansAnimalsCells
    70. Chan KH, Peiris JS, Lam SY, Poon LL, Yuen KY, Seto WH. The Effects of Temperature and Relative Humidity on the Viability of the SARS Coronavirus. Adv Virol. 2011; 2011:734690. PMID: 22312351.
      Citations: 296     
    71. Lau SK, Lee P, Tsang AK, Yip CC, Tse H, Lee RA, So LY, Lau YL, Chan KH, Woo PC, Yuen KY. Molecular epidemiology of human coronavirus OC43 reveals evolution of different genotypes over time and recent emergence of a novel genotype due to natural recombination. J Virol. 2011 Nov; 85(21):11325-37. PMID: 21849456.
      Citations: 115     Fields:    Translation:HumansCells
    72. Lau SK, Poon RW, Wong BH, Wang M, Huang Y, Xu H, Guo R, Li KS, Gao K, Chan KH, Zheng BJ, Woo PC, Yuen KY. Coexistence of different genotypes in the same bat and serological characterization of Rousettus bat coronavirus HKU9 belonging to a novel Betacoronavirus subgroup. J Virol. 2010 Nov; 84(21):11385-94. PMID: 20702646.
      Citations: 58     Fields:    Translation:AnimalsCells
    73. Lau SK, Li KS, Huang Y, Shek CT, Tse H, Wang M, Choi GK, Xu H, Lam CS, Guo R, Chan KH, Zheng BJ, Woo PC, Yuen KY. Ecoepidemiology and complete genome comparison of different strains of severe acute respiratory syndrome-related Rhinolophus bat coronavirus in China reveal bats as a reservoir for acute, self-limiting infection that allows recombination events. J Virol. 2010 Mar; 84(6):2808-19. PMID: 20071579.
      Citations: 127     Fields:    Translation:HumansAnimalsCells
    74. Tang BS, Chan KH, Cheng VC, Yuen KY. Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by SARS coronavirus and human coronavirus 229E. Hong Kong Med J. 2009 Dec; 15 Suppl 9:23-6. PMID: 20393221.
      Citations: 3     Fields:    Translation:HumansCells
    75. Nicholls JM, Peiris JS, Chan KH, Poon LM, Beh SL. Occult respiratory viral infections in coronial autopsies: a pilot project. Hong Kong Med J. 2009 Jun; 15(3 Suppl 4):13-5. PMID: 19509431.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    76. Woo PC, Lau SK, Lam CS, Lai KK, Huang Y, Lee P, Luk GS, Dyrting KC, Chan KH, Yuen KY. Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus. J Virol. 2009 Jan; 83(2):908-17. PMID: 18971277.
      Citations: 94     Fields:    Translation:AnimalsCells
    77. Lee PP, Wong WH, Leung GM, Chiu SS, Chan KH, Peiris JS, Lam TH, Lau YL. Risk-stratified seroprevalence of SARS coronavirus in children residing in a district with point-source outbreak compared to a low-risk area. Hong Kong Med J. 2008 Aug; 14 Suppl 4:17-20. PMID: 18708669.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    78. Fujimoto K, Chan KH, Takeda K, Lo KF, Leung RH, Okamoto T. Sensitive and specific enzyme-linked immunosorbent assay using chemiluminescence for detection of severe acute respiratory syndrome viral infection. J Clin Microbiol. 2008 Jan; 46(1):302-10. PMID: 18032623.
      Citations: 7     Fields:    Translation:HumansCells
    79. Cheuk DK, Tang IW, Chan KH, Woo PC, Peiris MJ, Chiu SS. Rhinovirus infection in hospitalized children in Hong Kong: a prospective study. Pediatr Infect Dis J. 2007 Nov; 26(11):995-1000. PMID: 17984805.
      Citations: 35     Fields:    Translation:HumansCells
    80. Chan KH, Sonnenberg K, Niedrig M, Lam SY, Pang CM, Chan KM, Ma SK, Seto WH, Peiris JS. Use of antibody avidity assays for diagnosis of severe acute respiratory syndrome coronavirus infection. Clin Vaccine Immunol. 2007 Nov; 14(11):1433-6. PMID: 17881505.
      Citations: 7     Fields:    Translation:HumansCells
    81. Lau SK, Yip CC, Que TL, Lee RA, Au-Yeung RK, Zhou B, So LY, Lau YL, Chan KH, Woo PC, Yuen KY. Clinical and molecular epidemiology of human bocavirus in respiratory and fecal samples from children in Hong Kong. J Infect Dis. 2007 Oct 01; 196(7):986-93. PMID: 17763318.
      Citations: 80     Fields:    Translation:HumansCells
    82. Lau SK, Woo PC, Li KS, Huang Y, Wang M, Lam CS, Xu H, Guo R, Chan KH, Zheng BJ, Yuen KY. Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome. Virology. 2007 Oct 25; 367(2):428-39. PMID: 17617433.
      Citations: 89     Fields:    Translation:AnimalsCells
    83. Woo PC, Wang M, Lau SK, Xu H, Poon RW, Guo R, Wong BH, Gao K, Tsoi HW, Huang Y, Li KS, Lam CS, Chan KH, Zheng BJ, Yuen KY. Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features. J Virol. 2007 Feb; 81(4):1574-85. PMID: 17121802.
      Citations: 155     Fields:    Translation:AnimalsCells
    84. Yip CW, Hon CC, Zeng F, Chow KY, Chan KH, Peiris JS, Leung FC. Naturally occurring anti-Escherichia coli protein antibodies in the sera of healthy humans cause analytical interference in a recombinant nucleocapsid protein-based enzyme-linked immunosorbent assay for serodiagnosis of severe acute respiratory syndrome. Clin Vaccine Immunol. 2007 Jan; 14(1):99-101. PMID: 17108287.
      Citations: 3     Fields:    Translation:HumansCells
    85. Zeng F, Hon CC, Yip CW, Law KM, Yeung YS, Chan KH, Malik Peiris JS, Leung FC. Quantitative comparison of the efficiency of antibodies against S1 and S2 subunit of SARS coronavirus spike protein in virus neutralization and blocking of receptor binding: implications for the functional roles of S2 subunit. FEBS Lett. 2006 Oct 16; 580(24):5612-20. PMID: 16989815.
      Citations: 17     Fields:    Translation:AnimalsCells
    86. Chu DKW, Poon LLM, Chan KH, Chen H, Guan Y, Yuen KY, Peiris JSM. Coronaviruses in bent-winged bats (Miniopterus spp.). J Gen Virol. 2006 Sep; 87(Pt 9):2461-2466. PMID: 16894183.
      Citations: 41     Fields:    Translation:AnimalsCells
    87. Woo PC, Lau SK, Yip CC, Huang Y, Tsoi HW, Chan KH, Yuen KY. Comparative analysis of 22 coronavirus HKU1 genomes reveals a novel genotype and evidence of natural recombination in coronavirus HKU1. J Virol. 2006 Jul; 80(14):7136-45. PMID: 16809319.
      Citations: 105     Fields:    Translation:HumansCells
    88. Lau SK, Woo PC, Yip CC, Tse H, Tsoi HW, Cheng VC, Lee P, Tang BS, Cheung CH, Lee RA, So LY, Lau YL, Chan KH, Yuen KY. Coronavirus HKU1 and other coronavirus infections in Hong Kong. J Clin Microbiol. 2006 Jun; 44(6):2063-71. PMID: 16757599.
      Citations: 194     Fields:    Translation:HumansCells
    89. Lee PP, Wong WH, Leung GM, Chiu SS, Chan KH, Peiris JS, Lam TH, Lau YL. Risk-stratified seroprevalence of severe acute respiratory syndrome coronavirus among children in Hong Kong. Pediatrics. 2006 Jun; 117(6):e1156-62. PMID: 16682490.
      Citations: 3     Fields:    Translation:HumansCells
    90. Woo PC, Lau SK, Li KS, Poon RW, Wong BH, Tsoi HW, Yip BC, Huang Y, Chan KH, Yuen KY. Molecular diversity of coronaviruses in bats. Virology. 2006 Jul 20; 351(1):180-7. PMID: 16647731.
      Citations: 156     Fields:    Translation:AnimalsCells
    91. Chan VS, Chan KY, Chen Y, Poon LL, Cheung AN, Zheng B, Chan KH, Mak W, Ngan HY, Xu X, Screaton G, Tam PK, Austyn JM, Chan LC, Yip SP, Peiris M, Khoo US, Lin CL. Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection. Nat Genet. 2006 Jan; 38(1):38-46. PMID: 16369534.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    92. Chan KH, Cheng VC, Woo PC, Lau SK, Poon LL, Guan Y, Seto WH, Yuen KY, Peiris JS. Serological responses in patients with severe acute respiratory syndrome coronavirus infection and cross-reactivity with human coronaviruses 229E, OC43, and NL63. Clin Diagn Lab Immunol. 2005 Nov; 12(11):1317-21. PMID: 16275947.
      Citations: 53     Fields:    Translation:HumansCells
    93. Woo PC, Lau SK, Tsoi HW, Huang Y, Poon RW, Chu CM, Lee RA, Luk WK, Wong GK, Wong BH, Cheng VC, Tang BS, Wu AK, Yung RW, Chen H, Guan Y, Chan KH, Yuen KY. Clinical and molecular epidemiological features of coronavirus HKU1-associated community-acquired pneumonia. J Infect Dis. 2005 Dec 01; 192(11):1898-907. PMID: 16267760.
      Citations: 128     Fields:    Translation:HumansCells
    94. Woo PC, Lau SK, Tsoi HW, Chen ZW, Wong BH, Zhang L, Chan JK, Wong LP, He W, Ma C, Chan KH, Ho DD, Yuen KY. SARS coronavirus spike polypeptide DNA vaccine priming with recombinant spike polypeptide from Escherichia coli as booster induces high titer of neutralizing antibody against SARS coronavirus. Vaccine. 2005 Oct 10; 23(42):4959-68. PMID: 15993989.
      Citations: 25     Fields:    Translation:AnimalsCells
    95. Lau SK, Woo PC, Li KS, Huang Y, Tsoi HW, Wong BH, Wong SS, Leung SY, Chan KH, Yuen KY. Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):14040-5. PMID: 16169905.
      Citations: 655     Fields:    Translation:AnimalsCells
    96. Woo PC, Lau SK, Wong BH, Tsoi HW, Fung AM, Kao RY, Chan KH, Peiris JS, Yuen KY. Differential sensitivities of severe acute respiratory syndrome (SARS) coronavirus spike polypeptide enzyme-linked immunosorbent assay (ELISA) and SARS coronavirus nucleocapsid protein ELISA for serodiagnosis of SARS coronavirus pneumonia. J Clin Microbiol. 2005 Jul; 43(7):3054-8. PMID: 16000415.
      Citations: 56     Fields:    Translation:HumansCells
    97. Lau SK, Che XY, Woo PC, Wong BH, Cheng VC, Woo GK, Hung IF, Poon RW, Chan KH, Peiris JS, Yuen KY. SARS coronavirus detection methods. Emerg Infect Dis. 2005 Jul; 11(7):1108-11. PMID: 16022791.
      Citations: 20     Fields:    Translation:HumansCells
    98. Woo PC, Lau SK, Huang Y, Tsoi HW, Chan KH, Yuen KY. Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia. Arch Virol. 2005 Nov; 150(11):2299-311. PMID: 15986174.
      Citations: 26     Fields:    Translation:HumansCells
    99. Cheung CY, Poon LL, Ng IH, Luk W, Sia SF, Wu MH, Chan KH, Yuen KY, Gordon S, Guan Y, Peiris JS. Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis. J Virol. 2005 Jun; 79(12):7819-26. PMID: 15919935.
      Citations: 207     Fields:    Translation:HumansAnimalsCells
    100. Chiu SS, Chan KH, Chu KW, Kwan SW, Guan Y, Poon LL, Peiris JS. Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China. Clin Infect Dis. 2005 Jun 15; 40(12):1721-9. PMID: 15909257.
      Citations: 140     Fields:    Translation:HumansCells
    101. Tang BS, Chan KH, Cheng VC, Woo PC, Lau SK, Lam CC, Chan TL, Wu AK, Hung IF, Leung SY, Yuen KY. Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by severe acute respiratory syndrome coronavirus and human coronavirus 229E. J Virol. 2005 May; 79(10):6180-93. PMID: 15858003.
      Citations: 55     Fields:    Translation:HumansCells
    102. Yam WC, Chan KH, Chow KH, Poon LL, Lam HY, Yuen KY, Seto WH, Peiris JS. Clinical evaluation of real-time PCR assays for rapid diagnosis of SARS coronavirus during outbreak and post-epidemic periods. J Clin Virol. 2005 May; 33(1):19-24. PMID: 15797361.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    103. Ip WK, Chan KH, Law HK, Tso GH, Kong EK, Wong WH, To YF, Yung RW, Chow EY, Au KL, Chan EY, Lim W, Jensenius JC, Turner MW, Peiris JS, Lau YL. Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection. J Infect Dis. 2005 May 15; 191(10):1697-704. PMID: 15838797.
      Citations: 113     Fields:    Translation:HumansCells
    104. Poon LL, Chu DK, Chan KH, Wong OK, Ellis TM, Leung YH, Lau SK, Woo PC, Suen KY, Yuen KY, Guan Y, Peiris JS. Identification of a novel coronavirus in bats. J Virol. 2005 Feb; 79(4):2001-9. PMID: 15681402.
      Citations: 173     Fields:    Translation:AnimalsCells
    105. Woo PC, Lau SK, Chu CM, Chan KH, Tsoi HW, Huang Y, Wong BH, Poon RW, Cai JJ, Luk WK, Poon LL, Wong SS, Guan Y, Peiris JS, Yuen KY. Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia. J Virol. 2005 Jan; 79(2):884-95. PMID: 15613317.
      Citations: 634     Fields:    Translation:HumansCells
    106. Chu CM, Leung WS, Cheng VC, Chan KH, Lin AW, Chan VL, Lam JY, Chan KS, Yuen KY. Duration of RT-PCR positivity in severe acute respiratory syndrome. Eur Respir J. 2005 Jan; 25(1):12-4. PMID: 15640317.
      Citations: 13     Fields:    Translation:HumansCells
    107. Woo PC, Lau SK, Wong BH, Chan KH, Hui WT, Kwan GS, Peiris JS, Couch RB, Yuen KY. False-positive results in a recombinant severe acute respiratory syndrome-associated coronavirus (SARS-CoV) nucleocapsid enzyme-linked immunosorbent assay due to HCoV-OC43 and HCoV-229E rectified by Western blotting with recombinant SARS-CoV spike polypeptide. J Clin Microbiol. 2004 Dec; 42(12):5885-8. PMID: 15583332.
      Citations: 46     Fields:    Translation:HumansCells
    108. Chu CM, Poon LL, Cheng VC, Chan KS, Hung IF, Wong MM, Chan KH, Leung WS, Tang BS, Chan VL, Ng WL, Sim TC, Ng PW, Law KI, Tse DM, Peiris JS, Yuen KY. Initial viral load and the outcomes of SARS. CMAJ. 2004 Nov 23; 171(11):1349-52. PMID: 15557587.
      Citations: 80     Fields:    Translation:HumansCells
    109. Liang G, Chen Q, Xu J, Liu Y, Lim W, Peiris JS, Anderson LJ, Ruan L, Li H, Kan B, Di B, Cheng P, Chan KH, Erdman DD, Gu S, Yan X, Liang W, Zhou D, Haynes L, Duan S, Zhang X, Zheng H, Gao Y, Tong S, Li D, Fang L, Qin P, Xu W. Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China. Emerg Infect Dis. 2004 Oct; 10(10):1774-81. PMID: 15504263.
      Citations: 56     Fields:    Translation:HumansCells
    110. Chen F, Chan KH, Jiang Y, Kao RY, Lu HT, Fan KW, Cheng VC, Tsui WH, Hung IF, Lee TS, Guan Y, Peiris JS, Yuen KY. In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds. J Clin Virol. 2004 Sep; 31(1):69-75. PMID: 15288617.
      Citations: 199     Fields:    Translation:HumansCells
    111. Kao RY, Tsui WH, Lee TS, Tanner JA, Watt RM, Huang JD, Hu L, Chen G, Chen Z, Zhang L, He T, Chan KH, Tse H, To AP, Ng LW, Wong BC, Tsoi HW, Yang D, Ho DD, Yuen KY. Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics. Chem Biol. 2004 Sep; 11(9):1293-9. PMID: 15380189.
      Citations: 76     Fields:    Translation:AnimalsCells
    112. Hung IF, Cheng VC, Wu AK, Tang BS, Chan KH, Chu CM, Wong MM, Hui WT, Poon LL, Tse DM, Chan KS, Woo PC, Lau SK, Peiris JS, Yuen KY. Viral loads in clinical specimens and SARS manifestations. Emerg Infect Dis. 2004 Sep; 10(9):1550-7. PMID: 15498155.
      Citations: 117     Fields:    Translation:HumansCellsPHPublic Health
    113. Woo PC, Lau SK, Wong BH, Chan KH, Chu CM, Tsoi HW, Huang Y, Peiris JS, Yuen KY. Longitudinal profile of immunoglobulin G (IgG), IgM, and IgA antibodies against the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in patients with pneumonia due to the SARS coronavirus. Clin Diagn Lab Immunol. 2004 Jul; 11(4):665-8. PMID: 15242938.
      Citations: 75     Fields:    Translation:HumansCells
    114. Guan M, Chan KH, Peiris JS, Kwan SW, Lam SY, Pang CM, Chu KW, Chan KM, Chen HY, Phuah EB, Wong CJ. Evaluation and validation of an enzyme-linked immunosorbent assay and an immunochromatographic test for serological diagnosis of severe acute respiratory syndrome. Clin Diagn Lab Immunol. 2004 Jul; 11(4):699-703. PMID: 15242944.
      Citations: 11     Fields:    Translation:HumansCells
    115. Lau SK, Woo PC, Wong BH, Tsoi HW, Woo GK, Poon RW, Chan KH, Wei WI, Peiris JS, Yuen KY. Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in sars patients by enzyme-linked immunosorbent assay. J Clin Microbiol. 2004 Jul; 42(7):2884-9. PMID: 15243033.
      Citations: 57     Fields:    Translation:HumansCells
    116. Poon LL, Wong BW, Chan KH, Leung CS, Yuen KY, Guan Y, Peiris JS. A one step quantitative RT-PCR for detection of SARS coronavirus with an internal control for PCR inhibitors. J Clin Virol. 2004 Jul; 30(3):214-7. PMID: 15135737.
      Citations: 22     Fields:    Translation:HumansCells
    117. Leung CW, Kwan YW, Ko PW, Chiu SS, Loung PY, Fong NC, Lee LP, Hui YW, Law HK, Wong WH, Chan KH, Peiris JS, Lim WW, Lau YL, Chiu MC. Severe acute respiratory syndrome among children. Pediatrics. 2004 Jun; 113(6):e535-43. PMID: 15173534.
      Citations: 57     Fields:    Translation:Humans
    118. Woo PC, Lau SK, Wong BH, Tsoi HW, Fung AM, Chan KH, Tam VK, Peiris JS, Yuen KY. Detection of specific antibodies to severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein for serodiagnosis of SARS coronavirus pneumonia. J Clin Microbiol. 2004 May; 42(5):2306-9. PMID: 15131220.
      Citations: 58     Fields:    Translation:HumansCells
    119. Poon LL, Leung CS, Tashiro M, Chan KH, Wong BW, Yuen KY, Guan Y, Peiris JS. Rapid detection of the severe acute respiratory syndrome (SARS) coronavirus by a loop-mediated isothermal amplification assay. Clin Chem. 2004 Jun; 50(6):1050-2. PMID: 15054079.
      Citations: 48     Fields:    Translation:HumansCells
    120. Zeng F, Chow KY, Hon CC, Law KM, Yip CW, Chan KH, Peiris JS, Leung FC. Characterization of humoral responses in mice immunized with plasmid DNAs encoding SARS-CoV spike gene fragments. Biochem Biophys Res Commun. 2004 Mar 19; 315(4):1134-9. PMID: 14985131.
      Citations: 27     Fields:    Translation:AnimalsCellsPHPublic Health
    121. Woo PC, Lau SK, Tsoi HW, Chan KH, Wong BH, Che XY, Tam VK, Tam SC, Cheng VC, Hung IF, Wong SS, Zheng BJ, Guan Y, Yuen KY. Relative rates of non-pneumonic SARS coronavirus infection and SARS coronavirus pneumonia. Lancet. 2004 Mar 13; 363(9412):841-5. PMID: 15031027.
      Citations: 80     Fields:    Translation:HumansCells
    122. Chu CM, Cheng VC, Hung IF, Wong MM, Chan KH, Chan KS, Kao RY, Poon LL, Wong CL, Guan Y, Peiris JS, Yuen KY. Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings. Thorax. 2004 Mar; 59(3):252-6. PMID: 14985565.
      Citations: 645     Fields:    Translation:HumansCTClinical Trials
    123. Haagmans BL, Kuiken T, Martina BE, Fouchier RA, Rimmelzwaan GF, van Amerongen G, van Riel D, de Jong T, Itamura S, Chan KH, Tashiro M, Osterhaus AD. Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques. Nat Med. 2004 Mar; 10(3):290-3. PMID: 14981511.
      Citations: 176     Fields:    Translation:HumansAnimalsCells
    124. Cheng VC, Hung IF, Tang BS, Chu CM, Wong MM, Chan KH, Wu AK, Tse DM, Chan KS, Zheng BJ, Peiris JS, Sung JJ, Yuen KY. Viral replication in the nasopharynx is associated with diarrhea in patients with severe acute respiratory syndrome. Clin Infect Dis. 2004 Feb 15; 38(4):467-75. PMID: 14765337.
      Citations: 51     Fields:    Translation:HumansCellsPHPublic Health
    125. Guan Y, Peiris JS, Zheng B, Poon LL, Chan KH, Zeng FY, Chan CW, Chan MN, Chen JD, Chow KY, Hon CC, Hui KH, Li J, Li VY, Wang Y, Leung SW, Yuen KY, Leung FC. Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome. Lancet. 2004 Jan 10; 363(9403):99-104. PMID: 14726162.
      Citations: 47     Fields:    Translation:HumansCellsPHPublic Health
    126. Poon LL, Chan KH, Wong OK, Cheung TK, Ng I, Zheng B, Seto WH, Yuen KY, Guan Y, Peiris JS. Detection of SARS coronavirus in patients with severe acute respiratory syndrome by conventional and real-time quantitative reverse transcription-PCR assays. Clin Chem. 2004 Jan; 50(1):67-72. PMID: 14709637.
      Citations: 51     Fields:    Translation:HumansCells
    127. Poon LL, Chan KH, Peiris JS. Crouching tiger, hidden dragon: the laboratory diagnosis of severe acute respiratory syndrome. Clin Infect Dis. 2004 Jan 15; 38(2):297-9. PMID: 14699466.
      Citations: 6     Fields:    Translation:HumansCells
    128. Poon LL, Chan KH, Wong OK, Yam WC, Yuen KY, Guan Y, Lo YM, Peiris JS. Early diagnosis of SARS coronavirus infection by real time RT-PCR. J Clin Virol. 2003 Dec; 28(3):233-8. PMID: 14522060.
      Citations: 81     Fields:    Translation:HumansCells
    129. Zhong NS, Zhong NS, Zheng BJ, Li YM, Xie ZH, Chan KH, Li PH, Tan SY, Chang Q, Xie JP, Liu XQ, Xu J, Li DX, Yuen KY, Guan Y. Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003. Lancet. 2003 Oct 25; 362(9393):1353-8. PMID: 14585636.
      Citations: 485     Fields:    Translation:HumansCellsPHPublic Health
    130. Yam WC, Chan KH, Poon LL, Guan Y, Yuen KY, Seto WH, Peiris JS. Evaluation of reverse transcription-PCR assays for rapid diagnosis of severe acute respiratory syndrome associated with a novel coronavirus. J Clin Microbiol. 2003 Oct; 41(10):4521-4. PMID: 14532176.
      Citations: 79     Fields:    Translation:HumansCells
    131. Zeng FY, Chan CW, Chan MN, Chen JD, Chow KY, Hon CC, Hui KH, Li J, Li VY, Wang CY, Wang PY, Guan Y, Zheng B, Poon LL, Chan KH, Yuen KY, Peiris JS, Leung FC. The complete genome sequence of severe acute respiratory syndrome coronavirus strain HKU-39849 (HK-39). Exp Biol Med (Maywood). 2003 Jul; 228(7):866-73. PMID: 12876307.
      Citations: 27     Fields:    Translation:Cells
    132. Poon LL, Wong OK, Chan KH, Luk W, Yuen KY, Peiris JS, Guan Y. Rapid diagnosis of a coronavirus associated with severe acute respiratory syndrome (SARS). Clin Chem. 2003 Jun; 49(6 Pt 1):953-5. PMID: 12765993.
      Citations: 57     Fields:    Translation:HumansCells
    133. Peiris JS, Chu CM, Cheng VC, Chan KS, Hung IF, Poon LL, Law KI, Tang BS, Hon TY, Chan CS, Chan KH, Ng JS, Zheng BJ, Ng WL, Lai RW, Guan Y, Yuen KY. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003 May 24; 361(9371):1767-72. PMID: 12781535.
      Citations: 944     Fields:    Translation:HumansCellsPHPublic Health
    134. Peiris JS, Lai ST, Poon LL, Guan Y, Yam LY, Lim W, Nicholls J, Yee WK, Yan WW, Cheung MT, Cheng VC, Chan KH, Tsang DN, Yung RW, Ng TK, Yuen KY. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet. 2003 Apr 19; 361(9366):1319-25. PMID: 12711465.
      Citations: 1117     Fields:    Translation:HumansCells
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