"Forkhead Box Protein O3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A forkhead box transcription factor and transcriptional activator which triggers type 1 programmed cell death (APOPTOSIS) in the absence of APOPTOSIS INHIBITING PROTEINS, including neuronal cell death induced by OXIDATIVE STRESS. It recognizes and binds to the DNA sequence 5'-(AG)TAAA(TC)A-3' and also functions in post-transcriptional regulation of the c-MYC PROTO-ONCOGENE.
| Descriptor ID |
D000071316
|
| MeSH Number(s) |
D12.776.260.950.249.125 D12.776.930.977.249.125
|
| Concept/Terms |
Forkhead Box Protein O3- Forkhead Box Protein O3
- Forkhead in Rhabdomyosarcoma-Like 1 Protein
- Forkhead in Rhabdomyosarcoma Like 1 Protein
- FOXO3 Protein
- Protein, FOXO3
|
Below are MeSH descriptors whose meaning is more general than "Forkhead Box Protein O3".
Below are MeSH descriptors whose meaning is more specific than "Forkhead Box Protein O3".
This graph shows the total number of publications written about "Forkhead Box Protein O3" by people in this website by year, and whether "Forkhead Box Protein O3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 5 | 3 | 8 |
| 2018 | 5 | 3 | 8 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Forkhead Box Protein O3" by people in Profiles.
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A review for natural polysaccharides with anti-pulmonary fibrosis properties, which may benefit to patients infected by 2019-nCoV. Carbohydr Polym. 2020 Nov 01; 247:116740.
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Mitochondrial Morphology, Dynamics, and Function in Human Pressure Overload or Ischemic Heart Disease With Preserved or Reduced Ejection Fraction. Circ Heart Fail. 2019 02; 12(2):e005131.
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AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis. Dev Cell. 2018 12 03; 47(5):592-607.e6.
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Inactivation of Stat3 and crosstalk of miRNA155-5p and FOXO3a contribute to the induction of IGFBP1 expression by beta-elemene in human lung cancer. Exp Mol Med. 2018 09 12; 50(9):1-14.
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Protective effects of 2,3,5,4-tetrahydroxystilbene-2-o-ß-D-glucoside against osteoporosis: Current knowledge and proposed mechanisms. Int J Rheum Dis. 2018 Aug; 21(8):1504-1513.
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High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway. J Exp Clin Cancer Res. 2018 Jul 31; 37(1):178.
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ROR?t-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells. Cancer Immunol Res. 2018 09; 6(9):1082-1092.
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The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer. Nucleic Acids Res. 2018 06 20; 46(11):5587-5600.
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miR-9 upregulation leads to inhibition of erythropoiesis by repressing FoxO3. Sci Rep. 2018 04 25; 8(1):6519.
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Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy. Cell Death Dis. 2018 02 14; 9(2):231.