Copper-transporting ATPases
"Copper-transporting ATPases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
P-type ATPases which transport copper ions across membranes in prokaryotic and eukaryotic cells. They possess a conserved CYSTEINE-HISTIDINE-SERINE (CPx) amino acid motif within their transmembrane helices that functions in cation translocation and catalytic activation, and an N-terminal copper-binding CxxC motif that regulates enzyme activity. They play essential roles in intracellular copper homeostasis through regulating the uptake, efflux and storage of copper ions, and in cuproprotein biosynthesis.
| Descriptor ID |
D000073840
|
| MeSH Number(s) |
D08.811.277.040.025.314.500 D12.776.157.530.450.250.656 D12.776.157.530.813.500 D12.776.543.585.450.250.656 D12.776.543.585.813.500
|
| Concept/Terms |
Copper-transporting ATPases- Copper-transporting ATPases
- ATPases, Copper-transporting
- Copper transporting ATPases
- Cu(+)-transporting ATPases
- Copper-transporting Adenosine Triphosphatases
- Adenosine Triphosphatases, Copper-transporting
- Copper transporting Adenosine Triphosphatases
- Triphosphatases, Copper-transporting Adenosine
- Copper-transporting ATPase
- ATPase, Copper-transporting
- Copper transporting ATPase
- Cu-transporting ATPases
- ATPases, Cu-transporting
- Cu transporting ATPases
Wilson Disease Protein- Wilson Disease Protein
- ATP7B Cu-binding P type ATPase
- ATP7B Cu binding P type ATPase
- Copper-transporting ATPase 2
- Copper transporting ATPase 2
- ATPase, Cu++ transporting, beta Polypeptide (Wilson Disease)
- Wilson Disease Cu-binding P Type ATPase
- Wilson Disease Cu binding P Type ATPase
Copper-transporting ATPase 1- Copper-transporting ATPase 1
- ATPase 1, Copper-transporting
- Copper transporting ATPase 1
- Copper Pump 1
- Menkes Disease-associated Protein
- Menkes Disease associated Protein
- ATP7A Protein
- ATPase Copper Transporting alpha
Pineal Night-specific ATPase- Pineal Night-specific ATPase
- ATPase, Pineal Night-specific
- Night-specific ATPase, Pineal
- Pineal Night specific ATPase
- PINA Enzyme
|
Below are MeSH descriptors whose meaning is more general than "Copper-transporting ATPases".
Below are MeSH descriptors whose meaning is more specific than "Copper-transporting ATPases".
This graph shows the total number of publications written about "Copper-transporting ATPases" by people in this website by year, and whether "Copper-transporting ATPases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 1 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Copper-transporting ATPases" by people in Profiles.
-
Melatonin: A hypothesis regarding its use to treat Wilson disease. Med Hypotheses. 2019 Dec; 133:109408.
-
Wilson's disease: A new perspective review on its genetics, diagnosis and treatment. Front Biosci (Elite Ed). 2019 06 01; 11(1):166-185.
-
Plasma transfusion combined with chelating therapy alleviates fulminant Wilson's disease with a single Arg778Leu heterozygote mutation. Ann Hepatol. 2019 Mar - Apr; 18(2):393-396.
-
Metallothionein is elevated in liver and duodenum of Atp7b(-/-) mice. Biometals. 2018 08; 31(4):617-625.
-
Pili torti, pale and elastic skin, and severe neurological impairment. J Dtsch Dermatol Ges. 2018 Mar; 16(3):360-363.
-
Severe dysfunction of respiratory chain and cholesterol metabolism in Atp7b(-/-) mice as a model for Wilson disease. Biochim Biophys Acta. 2011 Dec; 1812(12):1607-15.
-
Genetic analysis of BIRC4/XIAP as a putative modifier gene of Wilson disease. J Inherit Metab Dis. 2010 Dec; 33 Suppl 3:S233-40.