"P-type ATPases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly conserved family of ATPases that facilitate the transport of lipids and cations across the plasma membrane. Structurally, they are elongated ALPHA-HELICES constituting five functionally distinct domains: three cytoplasmic domains A, N, and P which contain the catalytic sites, and two transmembrane domains. The N domain phosphorylates the P-domain at an invariant ASPARTATE residue, which, in turn, is dephosphorylated by the A domain. The phosphorylation and dephosphorylation cycles drive conformational changes in the protein between two states (E1 and E2), which allow the substrate to access the other side of the membrane.
| Descriptor ID |
D000073779
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| MeSH Number(s) |
D08.811.277.040.025.314 D12.776.157.530.813 D12.776.543.585.813
|
| Concept/Terms |
P-type ATPases- P-type ATPases
- ATPases, P-type
- P type ATPases
- Phosphorylation-type ATPases
- ATPases, Phosphorylation-type
- Phosphorylation type ATPases
- P-type Adenosine Triphosphatases
- Adenosine Triphosphatases, P-type
- P type Adenosine Triphosphatases
- Triphosphatases, P-type Adenosine
- Phosphorylation-type Adenosine Triphosphatases
- Adenosine Triphosphatases, Phosphorylation-type
- Phosphorylation type Adenosine Triphosphatases
- Triphosphatases, Phosphorylation-type Adenosine
- E1-E2 ATPases
- ATPases, E1-E2
- E1 E2 ATPases
|
Below are MeSH descriptors whose meaning is more general than "P-type ATPases".
Below are MeSH descriptors whose meaning is more specific than "P-type ATPases".
This graph shows the total number of publications written about "P-type ATPases" by people in this website by year, and whether "P-type ATPases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "P-type ATPases" by people in Profiles.
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Role of P-type ATPase metal transporters and plant immunity induced by jasmonic acid against Lead (Pb) toxicity in tomato. Ecotoxicol Environ Saf. 2019 Jun 15; 174:283-294.