"NADPH Oxidase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
| Descriptor ID |
D000074662
|
| MeSH Number(s) |
D08.811.682.608.575.875 D12.776.331.894.875 D12.776.543.653.875
|
| Concept/Terms |
NADPH Oxidase 2- NADPH Oxidase 2
- Oxidase 2, NADPH
- Chronic Granulomatous Disease Protein
- GP91-PHOX Protein
- GP91 PHOX Protein
- CYBB Protein
- Cytochrome B-245 Beta Chain
- Cytochrome B 245 Beta Chain
- NOX2 Protein
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 2".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 2".
This graph shows the total number of publications written about "NADPH Oxidase 2" by people in this website by year, and whether "NADPH Oxidase 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 5 | 4 | 9 |
| 2018 | 8 | 2 | 10 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "NADPH Oxidase 2" by people in Profiles.
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NOX-Dependent Signaling Dysregulation in Severe COVID-19: Clues to Effective Treatments. Front Cell Infect Microbiol. 2020; 10:608435.
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COVID-19 and cardiovascular injury: A role for oxidative stress and antioxidant treatment? Int J Cardiol. 2020 08 01; 312:136.
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Nox2 activation in Covid-19. Redox Biol. 2020 09; 36:101655.
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Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus. Prog Cardiovasc Dis. 2020 May - Jun; 63(3):383-385.
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Passive Smoking Exacerbates Nicotinamide-Adenine Dinucleotide Phosphate Oxidase Isoform 2-Induced Oxidative Stress and Arterial Dysfunction in Children with Persistent Allergic Rhinitis. J Pediatr. 2018 11; 202:252-257.
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A novel mutation in CYBB gene in a patient with chronic colitis and recurrent pneumonia due to X-linked chronic granulomatous disease. Pediatr Blood Cancer. 2018 12; 65(12):e27382.
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Hazelnut and cocoa spread improves flow-mediated dilatation in smokers. Intern Emerg Med. 2018 Dec; 13(8):1211-1217.
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Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling. J Clin Invest. 2018 07 02; 128(7):3088-3101.
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Gut-derived lipopolysaccharides increase post-prandial oxidative stress via Nox2 activation in patients with impaired fasting glucose tolerance: effect of extra-virgin olive oil. Eur J Nutr. 2019 Mar; 58(2):843-851.
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Oleuropein, a component of extra virgin olive oil, lowers postprandial glycaemia in healthy subjects. Br J Clin Pharmacol. 2018 07; 84(7):1566-1574.