"NADPH Oxidase 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that is strongly expressed in the kidney. It forms a complex with CYBA-P22PHOX and produces intracellular SUPEROXIDES that may regulate cellular signaling in APOPTOSIS; BONE RESORPTION; and NF-KAPPA B activation.
| Descriptor ID |
D000074663
|
| MeSH Number(s) |
D08.811.682.608.575.937 D12.776.331.894.937 D12.776.543.653.937
|
| Concept/Terms |
NADPH Oxidase 4- NADPH Oxidase 4
- Oxidase 4, NADPH
- Renal NAD(P)H Oxidase
- Nox4 Protein
- Renox NAD(P)H Oxidase
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 4".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 4".
This graph shows the total number of publications written about "NADPH Oxidase 4" by people in this website by year, and whether "NADPH Oxidase 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 6 | 1 | 7 |
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Below are the most recent publications written about "NADPH Oxidase 4" by people in Profiles.
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Transforming growth factor ß1-induced collagen production in myofibroblasts is mediated by reactive oxygen species derived from NADPH oxidase 4. Biochem Biophys Res Commun. 2018 11 30; 506(3):557-562.
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A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes. Acta Ophthalmol. 2018 Nov; 96(7):e811-e819.
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Fenofibrate improves renal function by amelioration of NOX-4, IL-18, and p53 expression in an experimental model of diabetic nephropathy. J Cell Biochem. 2018 09; 119(9):7458-7469.
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Crocin improves renal function by declining Nox-4, IL-18, and p53 expression levels in an experimental model of diabetic nephropathy. J Cell Biochem. 2018 07; 119(7):6080-6093.
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Liraglutide attenuates NLRP3 inflammasome-dependent pyroptosis via regulating SIRT1/NOX4/ROS pathway in H9c2 cells. Biochem Biophys Res Commun. 2018 05 05; 499(2):267-272.
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Both cardiomyocyte and endothelial cell Nox4 mediate protection against hemodynamic overload-induced remodelling. Cardiovasc Res. 2018 Mar 01; 114(3):401-408.
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Oxidative stress caused by activation of NADPH oxidase 4 promotes contrast-induced acute kidney injury. PLoS One. 2018; 13(1):e0191034.
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Puerarin attenuates diabetic kidney injury through the suppression of NOX4 expression in podocytes. Sci Rep. 2017 11 06; 7(1):14603.
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Protective effects of probucol on Ox-LDL-induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells via LOX-1/ROS/MAPK signaling. Mol Med Rep. 2018 Jan; 17(1):1289-1296.
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Functional Role of Nox4 in Autophagy. Adv Exp Med Biol. 2017; 982:307-326.