Transcriptional Regulator ERG
"Transcriptional Regulator ERG" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trans-activator and member of the erythroblast transformation-specific family of transcriptions factors that contain a characteristic ETS MOTIF. It is required for PLATELET CELL ADHESION to the subendothelium and associates with CHIMERIC ONCOGENE PROTEINS in PROSTATE CANCER; EWING'S SARCOMA; and ACUTE MYELOID LEUKEMIA.
| Descriptor ID |
D000071230
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| MeSH Number(s) |
D12.776.260.755.100 D12.776.930.900.625
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| Concept/Terms |
Transcriptional Regulator ERG- Transcriptional Regulator ERG
- Transforming Protein ERG
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
- V Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein
- V Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcriptional Regulator ERG".
Below are MeSH descriptors whose meaning is more specific than "Transcriptional Regulator ERG".
This graph shows the total number of publications written about "Transcriptional Regulator ERG" by people in this website by year, and whether "Transcriptional Regulator ERG" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 4 | 5 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcriptional Regulator ERG" by people in Profiles.
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Genetic Associations With Plasma Angiotensin Converting Enzyme 2 Concentration: Potential Relevance to COVID-19 Risk. Circulation. 2020 09 15; 142(11):1117-1119.
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TMPRSS2: Potential Biomarker for COVID-19 Outcomes. J Clin Pharmacol. 2020 07; 60(7):801-807.
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Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML: a retrospective study by the I-BFM Study Group. Blood. 2018 10 11; 132(15):1584-1592.
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Re: Ken J. Kron, Alexander Murison, Stanley Zhou, et al. TMPRSS2-ERG Fusion Co-opts Master Transcription Factors and Activates NOTCH Signaling in Primary Prostate Cancer. Nat Genet 2017;49:1336-45. Eur Urol. 2018 04; 73(4):e106-e107.
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High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia. Oncotarget. 2017 Jun 27; 8(26):42398-42413.
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ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis. Nature. 2017 06 29; 546(7660):671-675.
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Synergistic Activity with NOTCH Inhibition and Androgen Ablation in ERG-Positive Prostate Cancer Cells. Mol Cancer Res. 2017 10; 15(10):1308-1317.
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ETS Related Gene mediated Androgen Receptor Aggregation and Endoplasmic Reticulum Stress in Prostate Cancer Development. Sci Rep. 2017 04 24; 7(1):1109.