"Zinc Finger Protein Gli2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME.
| Descriptor ID |
D000075746
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| MeSH Number(s) |
D12.776.260.755.925 D12.776.930.900.850
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Zinc Finger Protein Gli2".
Below are MeSH descriptors whose meaning is more specific than "Zinc Finger Protein Gli2".
This graph shows the total number of publications written about "Zinc Finger Protein Gli2" by people in this website by year, and whether "Zinc Finger Protein Gli2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Zinc Finger Protein Gli2" by people in Profiles.
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Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling. Proc Natl Acad Sci U S A. 2018 02 06; 115(6):1370-1375.
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Alcohol Reduces Arterial Remodeling by Inhibiting Sonic Hedgehog-Stimulated Stem Cell Antigen-1 Positive Progenitor Stem Cell Expansion. Alcohol Clin Exp Res. 2017 Dec; 41(12):2051-2065.
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Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development. J Biol Chem. 2017 09 22; 292(38):15814-15825.