"THP-1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A human leukemia monocytic cell line derived from a patient with LEUKEMIA, MONOCYTIC, ACUTE. It is used as a model to study the function of MONOCYTES and MACROPHAGES, their signaling pathways, nutrient and drug transport.
| Descriptor ID |
D000074084
|
| MeSH Number(s) |
A11.251.210.190.815 A11.251.860.180.815
|
| Concept/Terms |
THP-1 Cells- THP-1 Cells
- Cell, THP-1
- Cells, THP-1
- THP 1 Cells
- THP-1 Cell
- THP-1 Cell Line
- Cell Line, THP-1
- Cell Lines, THP-1
- THP 1 Cell Line
- THP-1 Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "THP-1 Cells".
Below are MeSH descriptors whose meaning is more specific than "THP-1 Cells".
This graph shows the total number of publications written about "THP-1 Cells" by people in this website by year, and whether "THP-1 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 17 | 17 |
| 2018 | 0 | 28 | 28 |
| 2019 | 0 | 8 | 8 |
| 2020 | 0 | 4 | 4 |
| 2021 | 0 | 5 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "THP-1 Cells" by people in Profiles.
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HIF-1a promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19. Signal Transduct Target Ther. 2021 08 18; 6(1):308.
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SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage. EMBO J. 2021 09 15; 40(18):e108249.
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SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation. Nat Commun. 2021 08 02; 12(1):4664.
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RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes. Cell Death Dis. 2021 07 23; 12(8):732.
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CAR Macrophages for SARS-CoV-2 Immunotherapy. Front Immunol. 2021; 12:669103.
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Poly-l-lysine Glycoconjugates Inhibit DC-SIGN-mediated Attachment of Pandemic Viruses. ChemMedChem. 2021 08 05; 16(15):2345-2353.
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SARS-CoV-2/ACE2 Interaction Suppresses IRAK-M Expression and Promotes Pro-Inflammatory Cytokine Production in Macrophages. Front Immunol. 2021; 12:683800.
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TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages. J Innate Immun. 2021; 13(6):345-358.
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TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions. Theranostics. 2021; 11(15):7379-7390.
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Anti-TNF-a agents Modulate SARS-CoV-2 Receptors and Increase the Risk of Infection Through Notch-1 Signaling. Front Immunol. 2021; 12:641295.