"PC12 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.
| Descriptor ID |
D016716
|
| MeSH Number(s) |
A11.251.210.190.750 A11.251.860.180.750 A11.299.500
|
| Concept/Terms |
PC12 Cells- PC12 Cells
- PC12 Cell
- Pheochromocytoma Cell Line
- Cell Line, Pheochromocytoma
- Cell Lines, Pheochromocytoma
- Pheochromocytoma Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "PC12 Cells".
Below are MeSH descriptors whose meaning is more specific than "PC12 Cells".
This graph shows the total number of publications written about "PC12 Cells" by people in this website by year, and whether "PC12 Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 8 | 8 |
| 2018 | 1 | 12 | 13 |
| 2019 | 0 | 5 | 5 |
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Below are the most recent publications written about "PC12 Cells" by people in Profiles.
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Pivotal role of cAMP-PKA-CREB signaling pathway in manganese-induced neurotoxicity in PC12 cells. Environ Toxicol. 2019 Sep; 34(9):1052-1062.
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Synthesis and Biological Activity of Some Benzochromenoquinolinones: Tacrine Analogs as Potent Anti-Alzheimer's Agents. Chem Biodivers. 2019 Apr; 16(4):e1800488.
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New benzyl pyridinium derivatives bearing 2,4-dioxochroman moiety as potent agents for treatment of Alzheimer's disease: Design, synthesis, biological evaluation, and docking study. Bioorg Chem. 2019 06; 87:506-515.
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A Bioinspired Platform for Effective Delivery of Protein Therapeutics to the Central Nervous System. Adv Mater. 2019 May; 31(18):e1807557.
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Inhibition of HDAC3 Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice In Vivo and In Vitro. J Diabetes Res. 2019; 2019:8520856.
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Butylene fipronil induces apoptosis in PC12 murine nervous cells via activation of p16-CDK4/6-cyclin D1 and mitochondrial apoptotic pathway. J Biochem Mol Toxicol. 2019 Mar; 33(3):e22264.
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Efficient treatment of Parkinson's disease using ultrasonography-guided rhFGF20 proteoliposomes. Drug Deliv. 2018 Nov; 25(1):1560-1569.
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Neuroprotective effect of naturally occurring RXR agonists isolated from Sophora tonkinensis Gagnep. on amyloid-ß-induced cytotoxicity in PC12 cells. J Nat Med. 2019 Jan; 73(1):154-162.
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Novel cinnamic acid-tryptamine hybrids as potent butyrylcholinesterase inhibitors: Synthesis, biological evaluation, and docking study. Arch Pharm (Weinheim). 2018 Oct; 351(10):e1800115.
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Isolation and Characterization of NP-POL Nonapeptide for Possible Therapeutic Use in Parkinson's Disease. Oxid Med Cell Longev. 2018; 2018:3760124.