NF-KappaB Inhibitor alpha
"NF-KappaB Inhibitor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes, sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm; and prevents NF-kappaB nuclear translocation and DNA binding.
| Descriptor ID |
D000072000
|
| MeSH Number(s) |
D12.644.360.365.500 D12.776.260.420.500 D12.776.476.381.500 D12.776.930.326.500
|
| Concept/Terms |
NF-KappaB Inhibitor alpha- NF-KappaB Inhibitor alpha
- Inhibitor alpha, NF-KappaB
- NF KappaB Inhibitor alpha
- alpha, NF-KappaB Inhibitor
- Major Histocompatibility Complex Enhancer-Binding Protein MAD3
- Major Histocompatibility Complex Enhancer Binding Protein MAD3
- IKappaB-alpha
- IKappaB alpha
- p40 Protein (IKappaB-alpha)
- I Kappa B-alpha Protein
- I Kappa B alpha Protein
- IKappaBalpha
|
Below are MeSH descriptors whose meaning is more general than "NF-KappaB Inhibitor alpha".
Below are MeSH descriptors whose meaning is more specific than "NF-KappaB Inhibitor alpha".
This graph shows the total number of publications written about "NF-KappaB Inhibitor alpha" by people in this website by year, and whether "NF-KappaB Inhibitor alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 3 | 5 |
| 2018 | 0 | 4 | 4 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "NF-KappaB Inhibitor alpha" by people in Profiles.
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Epigenetic Landscapes of Single-Cell Chromatin Accessibility and Transcriptomic Immune Profiles of T Cells in COVID-19 Patients. Front Immunol. 2021; 12:625881.
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EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2. PLoS One. 2020; 15(11):e0241739.
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Discovery of novel pyrazole derivatives as a potent anti-inflammatory agent in RAW264.7 cells via inhibition of NF-?B for possible benefit against SARS-CoV-2. J Biochem Mol Toxicol. 2021 Mar; 35(3):e22656.
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Activation of NF-?B induced by TRIMCyp showing a discrepancy between owl monkey and northern pig-tailed macaque. Mol Immunol. 2018 09; 101:627-634.
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Repurposing Thioridazine (TDZ) as an anti-inflammatory agent. Sci Rep. 2018 08 20; 8(1):12471.
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Bornyl acetate suppresses ox-LDL-induced attachment of THP-1 monocytes to endothelial cells. Biomed Pharmacother. 2018 Jul; 103:234-239.
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REDD-1 aggravates endotoxin-induced inflammation via atypical NF-?B activation. FASEB J. 2018 08; 32(8):4585-4599.
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Ctenopharyngodon idella IKKß interacts with PKR and I?Ba. Acta Biochim Biophys Sin (Shanghai). 2017 Aug 01; 49(8):729-736.
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Palmitoylethanolamide and Polydatin combination reduces inflammation and oxidative stress in vascular injury. Pharmacol Res. 2017 Sep; 123:83-92.
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Mechanisms of genotype-phenotype correlation in autosomal dominant anhidrotic ectodermal dysplasia with immune deficiency. J Allergy Clin Immunol. 2018 03; 141(3):1060-1073.e3.