Intracellular Signaling Peptides and Proteins
"Intracellular Signaling Peptides and Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors.
| Descriptor ID |
D047908
|
| MeSH Number(s) |
D12.644.360 D12.776.476
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Intracellular Signaling Peptides and Proteins".
Below are MeSH descriptors whose meaning is more specific than "Intracellular Signaling Peptides and Proteins".
This graph shows the total number of publications written about "Intracellular Signaling Peptides and Proteins" by people in this website by year, and whether "Intracellular Signaling Peptides and Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 2 | 3 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 18 | 35 | 53 |
| 2018 | 21 | 36 | 57 |
| 2019 | 6 | 6 | 12 |
| 2020 | 1 | 3 | 4 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Intracellular Signaling Peptides and Proteins" by people in Profiles.
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SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species. Emerg Microbes Infect. 2021 Dec; 10(1):178-195.
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Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target. Antiviral Res. 2021 10; 194:105167.
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Inflammasome activation at the crux of severe COVID-19. Nat Rev Immunol. 2021 11; 21(11):694-703.
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SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage. EMBO J. 2021 09 15; 40(18):e108249.
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Porcine Hemagglutinating Encephalomyelitis Virus Triggers Neural Autophagy Independently of ULK1. J Virol. 2021 09 09; 95(19):e0085121.
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HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response. Viruses. 2021 06 09; 13(6).
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Genome-wide screening of SARS-CoV-2 infection-related genes based on the blood leukocytes sequencing data set of patients with COVID-19. J Med Virol. 2021 09; 93(9):5544-5554.
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Pediatric LGI1 and CASPR2 autoimmunity associated with COVID 19: Morvan syndrome. J Neurol. 2021 Dec; 268(12):4492-4494.
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Baricitinib set to join the Covid-19 therapeutic arsenal? Rheumatology (Oxford). 2021 04 06; 60(4):1585-1587.
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Multifaceted Mechanisms of Action of Metformin Which Have Been Unraveled One after Another in the Long History. Int J Mol Sci. 2021 Mar 05; 22(5).