Transcription Factor HES-1
"Transcription Factor HES-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.
| Descriptor ID |
D000072056
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| MeSH Number(s) |
D12.776.260.103.844 D12.776.930.125.844
|
| Concept/Terms |
Transcription Factor HES-1- Transcription Factor HES-1
- HES-1, Transcription Factor
- Transcription Factor HES 1
- Hairy-Like Transcription Factor
- Hairy Like Transcription Factor
- Transcription Factor, Hairy-Like
- Hairy and Enhancer of Split 1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor HES-1".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor HES-1".
This graph shows the total number of publications written about "Transcription Factor HES-1" by people in this website by year, and whether "Transcription Factor HES-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor HES-1" by people in Profiles.
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Transplantation of bone marrow mesenchymal stem cells alleviates spinal cord injury via inhibiting Notch signaling. Eur Rev Med Pharmacol Sci. 2019 Aug; 23(3 Suppl):31-38.
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A reciprocal regulatory loop between TAZ/YAP and G-protein Gas regulates Schwann cell proliferation and myelination. Nat Commun. 2017 04 26; 8:15161.
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CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma. PLoS One. 2017; 12(4):e0173000.