"Smoothened Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A frizzled-like, G-protein-coupled receptor that associates with PATCHED RECEPTORS to transduce signals from HEDGEHOG PROTEINS and initiate hedgehog signaling to ZINC FINGER PROTEIN GLI1. It may normally inhibit signaling in the absence of SONIC HEDGEHOG PROTEIN binding to PATCHED RECEPTOR-1.
| Descriptor ID |
D000072086
|
| MeSH Number(s) |
D12.776.543.750.695.017.500 D12.776.543.750.850.500.500
|
| Concept/Terms |
Smoothened Receptor- Smoothened Receptor
- Receptor, Smoothened
- Smoothened Protein
- Smoothened Receptors
- Receptors, Smoothened
|
Below are MeSH descriptors whose meaning is more general than "Smoothened Receptor".
Below are MeSH descriptors whose meaning is more specific than "Smoothened Receptor".
This graph shows the total number of publications written about "Smoothened Receptor" by people in this website by year, and whether "Smoothened Receptor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Smoothened Receptor" by people in Profiles.
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Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling. Proc Natl Acad Sci U S A. 2018 02 06; 115(6):1370-1375.
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Recovery of taste organs and sensory function after severe loss from Hedgehog/Smoothened inhibition with cancer drug sonidegib. Proc Natl Acad Sci U S A. 2017 11 28; 114(48):E10369-E10378.