"Frizzled Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 to form receptors for WNT PROTEINS. Frizzled receptors often couple with HETEROTRIMERIC G PROTEINS and regulate the WNT SIGNALING PATHWAY.
| Descriptor ID |
D051157
|
| MeSH Number(s) |
D12.776.543.750.695.017 D12.776.543.750.850.500
|
| Concept/Terms |
Frizzled Receptors- Frizzled Receptors
- Frizzled Receptor
- Receptor, Frizzled
- Receptors, Frizzled
- Frizzled Proteins
|
Below are MeSH descriptors whose meaning is more general than "Frizzled Receptors".
Below are MeSH descriptors whose meaning is more specific than "Frizzled Receptors".
This graph shows the total number of publications written about "Frizzled Receptors" by people in this website by year, and whether "Frizzled Receptors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2018 | 3 | 2 | 5 |
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Below are the most recent publications written about "Frizzled Receptors" by people in Profiles.
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Wnt signaling in human and mouse breast cancer: Focusing on Wnt ligands, receptors and antagonists. Cancer Sci. 2018 Nov; 109(11):3368-3375.
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A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients. BMC Cancer. 2018 Jun 08; 18(1):646.
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MicroRNA-216b actively modulates diabetic angiopathy through inverse regulation on FZD5. Gene. 2018 Jun 05; 658:129-135.
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Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder. Transl Psychiatry. 2018 03 06; 8(1):55.
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Frizzled7 Promotes Epithelial-to-mesenchymal Transition and Stemness Via Activating Canonical Wnt/ß-catenin Pathway in Gastric Cancer. Int J Biol Sci. 2018; 14(3):280-293.
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Involvement of c-Fos in cell proliferation, migration, and invasion in osteosarcoma cells accompanied by altered expression of Wnt2 and Fzd9. PLoS One. 2017; 12(6):e0180558.