"Endonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the hydrolysis of the internal bonds and thereby the formation of polynucleotides or oligonucleotides from ribo- or deoxyribonucleotide chains. EC 3.1.-.
| Descriptor ID |
D004720
|
| MeSH Number(s) |
D08.811.277.352.355
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Endonucleases".
Below are MeSH descriptors whose meaning is more specific than "Endonucleases".
This graph shows the total number of publications written about "Endonucleases" by people in this website by year, and whether "Endonucleases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 11 | 6 | 17 |
| 2018 | 4 | 7 | 11 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endonucleases" by people in Profiles.
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Comparison of Antiviral Agents for Seasonal Influenza Outcomes in Healthy Adults and Children: A Systematic Review and Network Meta-analysis. JAMA Netw Open. 2021 08 02; 4(8):e2119151.
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Prediction of activity and specificity of CRISPR-Cpf1 using convolutional deep learning neural networks. BMC Bioinformatics. 2019 Jun 13; 20(1):332.
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Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents. N Engl J Med. 2018 09 06; 379(10):913-923.
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A Human DPP4-Knockin Mouse's Susceptibility to Infection by Authentic and Pseudotyped MERS-CoV. Viruses. 2018 08 23; 10(9).
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Single-Strand Break End Resection in Genome Integrity: Mechanism and Regulation by APE2. Int J Mol Sci. 2018 Aug 14; 19(8).
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Designer nuclease-mediated gene correction via homology-directed repair in an in vitro model of canine hemophilia B. J Gene Med. 2018 05; 20(5):e3020.
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Field-deployable viral diagnostics using CRISPR-Cas13. Science. 2018 04 27; 360(6387):444-448.
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Small molecules promote CRISPR-Cpf1-mediated genome editing in human pluripotent stem cells. Nat Commun. 2018 04 03; 9(1):1303.
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DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade. J Clin Invest. 2018 04 02; 128(4):1671-1687.
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APE2 promotes DNA damage response pathway from a single-strand break. Nucleic Acids Res. 2018 03 16; 46(5):2479-2494.