Aminoimidazole Carboxamide
"Aminoimidazole Carboxamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases.
| Descriptor ID |
D000620
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| MeSH Number(s) |
D03.383.129.308.030
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aminoimidazole Carboxamide".
Below are MeSH descriptors whose meaning is more specific than "Aminoimidazole Carboxamide".
This graph shows the total number of publications written about "Aminoimidazole Carboxamide" by people in this website by year, and whether "Aminoimidazole Carboxamide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 2 | 3 |
| 2018 | 2 | 1 | 3 |
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Below are the most recent publications written about "Aminoimidazole Carboxamide" by people in Profiles.
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Activation of AMPK alleviates cardiopulmonary bypass-induced cardiac injury via ameliorating acute cardiac glucose metabolic disorder. Cardiovasc Ther. 2018 Dec; 36(6):e12482.
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Metabolomics profiling of metformin-mediated metabolic reprogramming bypassing AMPKa. Metabolism. 2019 02; 91:18-29.
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The AMPK-activator AICAR in thyroid cancer: effects on CXCL8 secretion and on CXCL8-induced neoplastic cell migration. J Endocrinol Invest. 2018 Nov; 41(11):1275-1282.
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Effects of metformin on cell growth and AMPK activity in pituitary adenoma cell cultures, focusing on the interaction with adenylyl cyclase activating signals. Mol Cell Endocrinol. 2018 07 15; 470:60-74.
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AMPK Prevents Palmitic Acid-Induced Apoptosis and Lipid Accumulation in Cardiomyocytes. Lipids. 2017 09; 52(9):737-750.
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The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax. Haematologica. 2017 09; 102(9):1587-1593.