"Antithrombins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.
| Descriptor ID |
D000991
|
| MeSH Number(s) |
D27.505.519.389.745.800.449 D27.505.954.502.119.500
|
| Concept/Terms |
Antithrombins- Antithrombins
- Direct Thrombin Inhibitors
- Thrombin Inhibitors, Direct
- Direct Antithrombins
- Antithrombins, Direct
|
Below are MeSH descriptors whose meaning is more general than "Antithrombins".
Below are MeSH descriptors whose meaning is more specific than "Antithrombins".
This graph shows the total number of publications written about "Antithrombins" by people in this website by year, and whether "Antithrombins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 21 | 24 | 45 |
| 2018 | 24 | 11 | 35 |
| 2019 | 12 | 3 | 15 |
| 2020 | 6 | 5 | 11 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Antithrombins" by people in Profiles.
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Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia. Crit Care Med. 2021 09 01; 49(9):e870-e873.
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SARS-CoV-2 vaccine-induced immune thrombotic thrombocytopenia treated with immunoglobulin and argatroban. Lancet. 2021 06 26; 397(10293):e19.
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Immediate high-dose intravenous immunoglobulins followed by direct thrombin-inhibitor treatment is crucial for survival in Sars-Covid-19-adenoviral vector vaccine-induced immune thrombotic thrombocytopenia VITT with cerebral sinus venous and portal vein thrombosis. J Neurol. 2021 Dec; 268(12):4483-4485.
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Pulmonary embolism and thrombocytopenia following ChAdOx1 vaccination. Lancet. 2021 05 15; 397(10287):1842.
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COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A review of the potential mechanisms and proposed management. Sci Prog. 2021 Apr-Jun; 104(2):368504211025927.
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Antithrombin, COVID-19, and Fresh Frozen Plasma Treatment Turk J Haematol. 2021 06 01; 38(2):157-159.
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Prognostic Value of Antithrombin Levels in COVID-19 Patients and Impact of Fresh Frozen Plasma Treatment: A Retrospective Study Turk J Haematol. 2021 02 25; 38(1):15-21.
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Plasma Antithrombin Values Are Significantly Decreased in Coronavirus Disease 2019 (COVID-19) Patients with Severe Illness. Semin Thromb Hemost. 2021 06; 47(4):460-462.
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Coagulation profile of COVID-19 patients admitted to the ICU: An exploratory study. PLoS One. 2020; 15(12):e0243604.
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Thromboelastography clot strength profiles and effect of systemic anticoagulation in COVID-19 acute respiratory distress syndrome: a prospective, observational study. Eur Rev Med Pharmacol Sci. 2020 12; 24(23):12466-12479.