"Serpins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
| Descriptor ID |
D015843
|
| MeSH Number(s) |
D12.644.861 D12.776.872 D27.505.519.389.745.800.675
|
| Concept/Terms |
Serpins- Serpins
- Serpin Protease Inhibitors
- Inhibitors, Serpin Protease
- Protease Inhibitors, Serpin
- Serpin Peptidase Inhibitors
- Inhibitors, Serpin Peptidase
- Peptidase Inhibitors, Serpin
|
Below are MeSH descriptors whose meaning is more general than "Serpins".
Below are MeSH descriptors whose meaning is more specific than "Serpins".
This graph shows the total number of publications written about "Serpins" by people in this website by year, and whether "Serpins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 6 | 0 | 6 |
| 2018 | 5 | 0 | 5 |
| 2019 | 2 | 1 | 3 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serpins" by people in Profiles.
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Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19. Sci Rep. 2021 06 24; 11(1):13208.
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Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis. Commun Biol. 2021 05 17; 4(1):590.
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Using serpins cysteine protease cross-specificity to possibly trap SARS-CoV-2 Mpro with reactive center loop chimera. Clin Sci (Lond). 2020 09 18; 134(17):2235-2241.
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Elevations of serum cancer biomarkers correlate with severity of COVID-19. J Med Virol. 2020 10; 92(10):2036-2041.
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Liver infiltrating T cells regulate bile acid metabolism in experimental cholangitis. J Hepatol. 2019 10; 71(4):783-792.
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Squamous cell carcinoma-related antigen 2 level is a reliable indicator of severe psoriasis involving the face. G Ital Dermatol Venereol. 2019 Jun; 154(3):374-375.
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Squamous cell carcinoma antigen 1 is associated to poor prognosis in esophageal cancer through immune surveillance impairment and reduced chemosensitivity. Cancer Sci. 2019 May; 110(5):1552-1563.
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Bayesian Phylogeography and Pathogenic Characterization of Smallpox Based on HA, ATI, and CrmB Genes. Mol Biol Evol. 2018 11 01; 35(11):2607-2617.
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Genetic Regulation of Pigment Epithelium-Derived Factor (PEDF): An Exome-Chip Association Analysis in Chinese Subjects With Type 2 Diabetes. Diabetes. 2019 01; 68(1):198-206.
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Vaspin protects rats against myocardial ischemia/reperfusion injury (MIRI) through the TLR4/NF-?B signaling pathway. Eur J Pharmacol. 2018 Sep 15; 835:132-139.