"C-Peptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.
| Descriptor ID |
D002096
|
| MeSH Number(s) |
D06.472.699.587.200.500.250 D12.644.548.586.200.500.250
|
| Concept/Terms |
C-Peptide- C-Peptide
- C Peptide
- Connecting Peptide
- Proinsulin C-Peptide
- Proinsulin C Peptide
- C-Peptide, Proinsulin
- C Peptide, Proinsulin
|
Below are MeSH descriptors whose meaning is more general than "C-Peptide".
Below are MeSH descriptors whose meaning is more specific than "C-Peptide".
This graph shows the total number of publications written about "C-Peptide" by people in this website by year, and whether "C-Peptide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 2 | 6 | 8 |
| 2018 | 3 | 2 | 5 |
| 2019 | 3 | 2 | 5 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "C-Peptide" by people in Profiles.
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Acute hyperglycaemic crisis after vaccination against COVID-19: A case series. Diabet Med. 2021 11; 38(11):e14631.
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Quercetin/Zinc complex and stem cells: A new drug therapy to ameliorate glycometabolic control and pulmonary dysfunction in diabetes mellitus: Structural characterization and genetic studies. PLoS One. 2021; 16(3):e0246265.
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Prognostic bioindicators in severe COVID-19 patients. Cytokine. 2021 05; 141:155455.
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Glycemia, Beta-Cell Function and Sensitivity to Insulin in Mildly to Critically Ill Covid-19 Patients. Medicina (Kaunas). 2021 Jan 14; 57(1).
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Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity. J Clin Endocrinol Metab. 2019 11 01; 104(11):5703-5714.
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The effect of C-peptide on diabetic nephropathy: A review of molecular mechanisms. Life Sci. 2019 Nov 15; 237:116950.
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Sepsis uncouples serum C-peptide and insulin levels in critically ill patients with type 2 diabetes mellitus. Crit Care Resusc. 2019 Jun; 21(2):87-95.
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C-peptide and insulin assays with the Mindray CL-2000i: Precision and comparability with different methods. Clin Chim Acta. 2019 Aug; 495:210-214.
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The association of calcium channel blockers with ß-cell function in type 2 diabetic patients: A cross-sectional study. J Clin Hypertens (Greenwich). 2019 05; 21(5):638-647.
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Assessment of simple indices based on a single fasting blood sample as a tool to estimate beta-cell function after total pancreatectomy with islet autotransplantation - a prospective study. Transpl Int. 2019 03; 32(3):280-290.