"beta 2-Microglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.
| Descriptor ID |
D001613
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| MeSH Number(s) |
D12.776.124.790.223.100 D12.776.377.715.182.100
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta 2-Microglobulin".
Below are MeSH descriptors whose meaning is more specific than "beta 2-Microglobulin".
This graph shows the total number of publications written about "beta 2-Microglobulin" by people in this website by year, and whether "beta 2-Microglobulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1999 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2017 | 1 | 4 | 5 |
| 2018 | 2 | 4 | 6 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 2 | 3 |
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Below are the most recent publications written about "beta 2-Microglobulin" by people in Profiles.
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COVID-19-induced acute renal tubular injury associated with elevation of serum inflammatory cytokine. Clin Exp Nephrol. 2021 Nov; 25(11):1240-1246.
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Serum ß2-microglobulin levels in Coronavirus disease 2019 (Covid-19): Another prognosticator of disease severity? PLoS One. 2021; 16(3):e0247758.
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Direct hemoperfusion using a polymyxin B-immobilized polystyrene column for COVID-19. J Clin Apher. 2021 Jun; 36(3):313-321.
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Steroid-Responsive Encephalitis in Coronavirus Disease 2019. Ann Neurol. 2020 08; 88(2):423-427.
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The utility of beta-2-microglobulin testing as a human cellular control in COVID-19 testing. J Clin Virol. 2020 08; 129:104449.
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Discrepancy of Serological and Molecular Patterns of Circulating Epstein-Barr Virus Reactivation in Primary Sjögren's Syndrome. Front Immunol. 2019; 10:1153.
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Progression Risk Stratification of Asymptomatic Waldenström Macroglobulinemia. J Clin Oncol. 2019 06 01; 37(16):1403-1411.
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Recirculating peritoneal dialysis system using urease-fixed silk fibroin membrane filter with spherical carbonaceous adsorbent. Mater Sci Eng C Mater Biol Appl. 2019 Apr; 97:55-66.
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Venous thromboembolism in chronic lymphocytic leukemia: a Danish nationwide cohort study. Blood Adv. 2018 11 13; 2(21):3025-3034.
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Mechanical stresses induce paracrine ß-2 microglobulin from cardiomyocytes to activate cardiac fibroblasts through epidermal growth factor receptor. Clin Sci (Lond). 2018 08 31; 132(16):1855-1874.