"Wnt-5a Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Wnt protein and ligand for FRIZZLED RECEPTORS that may function as an inhibitor or activator of the WNT SIGNALING PATHWAY. For example, it activates signaling in the presence of Frizzled-4 but is inhibitory when coupled with ROR2 TYROSINE KINASE. It is required for axis formation during EMBRYOGENESIS and inhibits the proliferation, migration, and invasiveness of cancer cells.
| Descriptor ID |
D000071818
|
| MeSH Number(s) |
D12.776.467.984.050 D12.776.624.664.700.962 D23.529.984.050
|
| Concept/Terms |
Wnt-5a Protein- Wnt-5a Protein
- Wnt 5a Protein
- Wingless-Type MMTV Integration Site Family, Member 5A
- Wingless Type MMTV Integration Site Family, Member 5A
- Wnt5a Protein
|
Below are MeSH descriptors whose meaning is more general than "Wnt-5a Protein".
Below are MeSH descriptors whose meaning is more specific than "Wnt-5a Protein".
This graph shows the total number of publications written about "Wnt-5a Protein" by people in this website by year, and whether "Wnt-5a Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Wnt-5a Protein" by people in Profiles.
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Wnt5a and Wnt11 as acute respiratory distress syndrome biomarkers for severe acute respiratory syndrome coronavirus 2 patients. Eur Respir J. 2020 11; 56(5).
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Vitamin D3 supplementation improves serum SFRP5 and Wnt5a levels in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trial. Int J Vitam Nutr Res. 2018 Feb; 88(1-2):73-79.
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The Canonical but Not the Noncanonical Wnt Pathway Inhibits the Development of Allergic Airway Disease. J Immunol. 2018 10 01; 201(7):1855-1864.
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MicroRNA-1253 suppresses cell proliferation and invasion of non-small-cell lung carcinoma by targeting WNT5A. Cell Death Dis. 2018 02 07; 9(2):189.
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Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy. Sci Rep. 2017 06 14; 7(1):3490.
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Wnt5a is elevated in heart failure and affects cardiac fibroblast function. J Mol Med (Berl). 2017 07; 95(7):767-777.