Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase
"Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4.
| Descriptor ID |
D008240
|
| MeSH Number(s) |
D08.811.682.690.708.660
|
| Concept/Terms |
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase- Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase
- 2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine
- 5-Dioxygenase Procollagen-Lysine, 2-Oxoglutarate
- Procollagen Lysine, 2 Oxoglutarate 5 Dioxygenase
- Lysine 2-Oxoglutarate Dioxygenase
- 2-Oxoglutarate Dioxygenase, Lysine
- Dioxygenase, Lysine 2-Oxoglutarate
- Lysine 2 Oxoglutarate Dioxygenase
- Lysyl Hydroxylase
- Hydroxylase, Lysyl
- Protocollagen Lysyl Hydroxylase
- Hydroxylase, Protocollagen Lysyl
- Collagen Lysyl Hydroxylase
- Hydroxylase, Collagen Lysyl
- Lysine Hydroxylase
- Hydroxylase, Lysine
|
Below are MeSH descriptors whose meaning is more general than "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase".
Below are MeSH descriptors whose meaning is more specific than "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase".
This graph shows the total number of publications written about "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase" by people in this website by year, and whether "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase" by people in Profiles.
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Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis. Elife. 2018 07 03; 7.
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Inhibition of enzymes involved in collagen cross-linking reduces vascular smooth muscle cell calcification. FASEB J. 2018 08; 32(8):4459-4469.
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PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC. Cell Death Dis. 2017 10 26; 8(10):e3143.
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Asporin-deficient mice have tougher skin and altered skin glycosaminoglycan content and structure. PLoS One. 2017; 12(8):e0184028.
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A Chaperone Complex Formed by HSP47, FKBP65, and BiP Modulates Telopeptide Lysyl Hydroxylation of Type I Procollagen. J Bone Miner Res. 2017 Jun; 32(6):1309-1319.