"Fixatives" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents employed in the preparation of histologic or pathologic specimens for the purpose of maintaining the existing form and structure of all of the constituent elements. Great numbers of different agents are used; some are also decalcifying and hardening agents. They must quickly kill and coagulate living tissue.
Descriptor ID |
D005404
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MeSH Number(s) |
D27.720.355
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fixatives".
Below are MeSH descriptors whose meaning is more specific than "Fixatives".
This graph shows the total number of publications written about "Fixatives" by people in this website by year, and whether "Fixatives" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 |
2012 | 0 | 1 | 1 |
2017 | 2 | 0 | 2 |
2018 | 0 | 2 | 2 |
2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Fixatives" by people in Profiles.
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SARS-CoV-2 detection in formalin-fixed paraffin-embedded tissue specimens from surgical resection of tongue squamous cell carcinoma. J Clin Pathol. 2020 Nov; 73(11):754-757.
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Reappraisal of the Mawangdui Han Tomb Cadaver Thirty Years After Its Unearthing. Biopreserv Biobank. 2019 Apr; 17(2):98-104.
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Rift Valley Fever Viral RNA Detection by In Situ Hybridization in Formalin-Fixed, Paraffin-Embedded Tissues. Vector Borne Zoonotic Dis. 2019 07; 19(7):553-556.
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Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue. Diagn Pathol. 2018 Oct 20; 13(1):83.
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Caution: choice of fixative can influence the visualization of the location of a transcription factor in mammalian cells. Biotechniques. 2018 08; 65(2):65-69.
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RNAlater® is a viable storage option for avian influenza sampling in logistically challenging conditions. J Virol Methods. 2018 02; 252:32-36.
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A formalin-fixed paraffin-embedded (FFPE)-based prognostic signature to predict metastasis in clinically low risk stage I/II microsatellite stable colorectal cancer. Cancer Lett. 2017 09 10; 403:13-20.
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Clinical utility of DNA amplification and sequencing to identify a strain of Mycobacterium avium in paraffin-embedded, formalin-fixed biopsies from an immunosuppressed child. Pediatr Dev Pathol. 2012 Jul-Aug; 15(4):315-7.
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The impact of tissue fixatives on morphology and antibody-based protein profiling in tissues and cells. J Histochem Cytochem. 2010 Mar; 58(3):237-46.
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Inactivation of SARS coronavirus by means of povidone-iodine, physical conditions, and chemical reagents. Jpn J Vet Res. 2004 Nov; 52(3):105-12.