"Ionophores" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.
| Descriptor ID |
D007476
|
| MeSH Number(s) |
D27.505.519.562.374 D27.720.395
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ionophores".
Below are MeSH descriptors whose meaning is more specific than "Ionophores".
This graph shows the total number of publications written about "Ionophores" by people in this website by year, and whether "Ionophores" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Ionophores" by people in Profiles.
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Hypothesis of zinc ascorbate as best zinc ionophore for raising antiviral resistance against Covid-19. J Med Virol. 2021 09; 93(9):5205-5208.
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20-Week Study of Clinical Outcomes of Over-the-Counter COVID-19 Prophylaxis and Treatment. J Evid Based Integr Med. 2021 Jan-Dec; 26:2515690X211026193.
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Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro. Antiviral Res. 2021 01; 185:104988.
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Can food and food supplements be deployed in the fight against the COVID 19 pandemic? Biochim Biophys Acta Gen Subj. 2021 02; 1865(2):129801.
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A possible application of hinokitiol as a natural zinc ionophore and anti-infective agent for the prevention and treatment of COVID-19 and viral infections. Med Hypotheses. 2020 Dec; 145:110333.
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Zinc sulfate in combination with a zinc ionophore may improve outcomes in hospitalized COVID-19 patients. J Med Microbiol. 2020 Oct; 69(10):1228-1234.
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Endoplasmic reticulum as a potential therapeutic target for covid-19 infection management? Eur J Pharmacol. 2020 Sep 05; 882:173288.
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Novel Ionophores Active against La Crosse Virus Identified through Rapid Antiviral Screening. Antimicrob Agents Chemother. 2020 05 21; 64(6).
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Familial Mediterranean fever mutations are hypermorphic mutations that specifically decrease the activation threshold of the Pyrin inflammasome. Rheumatology (Oxford). 2018 01 01; 57(1):100-111.
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Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin. ACS Chem Biol. 2017 09 15; 12(9):2287-2295.