Complement C3b Inactivator Proteins
"Complement C3b Inactivator Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence.
Descriptor ID |
D003180
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MeSH Number(s) |
D12.776.124.486.274.920.325
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Concept/Terms |
Complement C3b Inactivator Proteins- Complement C3b Inactivator Proteins
- C3b Inhibitors
- Inhibitors, C3b
- Complement 3b Inactivators
- Inactivators, Complement 3b
- Complement C3b Inactivators
- Inactivators, Complement C3b
- Complement C3b Inhibitor Proteins
- Conglutinogen Activating Factors
- Factors, Conglutinogen Activating
- C3b Inactivators
- Inactivators, C3b
- Complement 3b Inhibitors
- Inhibitors, Complement 3b
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Below are MeSH descriptors whose meaning is more general than "Complement C3b Inactivator Proteins".
Below are MeSH descriptors whose meaning is more specific than "Complement C3b Inactivator Proteins".
This graph shows the total number of publications written about "Complement C3b Inactivator Proteins" by people in this website by year, and whether "Complement C3b Inactivator Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 |
2017 | 2 | 0 | 2 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement C3b Inactivator Proteins" by people in Profiles.
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Case Report: Severe Complement-Mediated Thrombotic Microangiopathy in IgG4-Related Disease Secondary to Anti-Factor H IgG4 Autoantibodies. Front Immunol. 2020; 11:604759.
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Response to Comment on "Self versus Nonself Discrimination by the Soluble Complement Regulators Factor H and FHL-1". J Immunol. 2019 10 15; 203(8):2029-2030.
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Factor H Competitor Generated by Gene Conversion Events Associates with Atypical Hemolytic Uremic Syndrome. J Am Soc Nephrol. 2018 01; 29(1):240-249.
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Circulating complement factor H-related proteins 1 and 5 correlate with disease activity in IgA nephropathy. Kidney Int. 2017 10; 92(4):942-952.
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Association of CFHR1 homozygous deletion with acute myelogenous leukemia in the European population. Leuk Lymphoma. 2016 May; 57(5):1234-7.