Specific Pathogen-Free Organisms
"Specific Pathogen-Free Organisms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Animals or humans raised in the absence of a particular disease-causing virus or other microorganism. Less frequently plants are cultivated pathogen-free.
| Descriptor ID |
D013047
|
| MeSH Number(s) |
G06.320.676
|
| Concept/Terms |
Specific Pathogen-Free Organisms- Specific Pathogen-Free Organisms
- Organism, Specific Pathogen-Free
- Organisms, Specific Pathogen-Free
- Pathogen-Free Organism, Specific
- Pathogen-Free Organisms, Specific
- Specific Pathogen Free Organisms
- Specific Pathogen-Free Organism
- Pathogen-Free Organisms
- Organism, Pathogen-Free
- Organisms, Pathogen-Free
- Pathogen Free Organisms
- Pathogen-Free Organism
|
Below are MeSH descriptors whose meaning is more general than "Specific Pathogen-Free Organisms".
Below are MeSH descriptors whose meaning is more specific than "Specific Pathogen-Free Organisms".
This graph shows the total number of publications written about "Specific Pathogen-Free Organisms" by people in this website by year, and whether "Specific Pathogen-Free Organisms" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2017 | 0 | 10 | 10 |
| 2018 | 0 | 7 | 7 |
| 2019 | 1 | 3 | 4 |
| 2020 | 0 | 5 | 5 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Specific Pathogen-Free Organisms" by people in Profiles.
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A human cell-based SARS-CoV-2 vaccine elicits potent neutralizing antibody responses and protects mice from SARS-CoV-2 challenge. Emerg Microbes Infect. 2021 Dec; 10(1):1555-1573.
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Clinical and Histopathologic Features of a Feline SARS-CoV-2 Infection Model Are Analogous to Acute COVID-19 in Humans. Viruses. 2021 08 05; 13(8).
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Nonhuman primate models for SARS-CoV-2 Research: Managing demand for specific-pathogen-free (SPF) animals. Lab Anim (NY). 2021 08; 50(8):200-201.
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Senolytics reduce coronavirus-related mortality in old mice. Science. 2021 07 16; 373(6552).
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Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 via Close Contact and Respiratory Droplets Among Human Angiotensin-Converting Enzyme 2 Mice. J Infect Dis. 2020 07 23; 222(4):551-555.
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A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS. Cell. 2020 08 06; 182(3):722-733.e11.
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Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment. Cell. 2020 08 06; 182(3):734-743.e5.
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A highly pathogenic GI-19 lineage infectious bronchitis virus originated from multiple recombination events with broad tissue tropism. Virus Res. 2020 08; 285:198002.
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Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development. EBioMedicine. 2020 May; 55:102743.
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Methylcitrate cycle gene MCD is essential for the virulence of Talaromyces marneffei. Med Mycol. 2020 Apr 01; 58(3):351-361.