"Thioguanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
| Descriptor ID |
D013866
|
| MeSH Number(s) |
D03.633.100.759.854
|
| Concept/Terms |
Thioguanine- Thioguanine
- 2-Amino-6-Purinethiol
- 2 Amino 6 Purinethiol
- Tioguanine
- 6-Thioguanine
- 6 Thioguanine
Tabloid- Tabloid
- Thioguanine Tabloid
- Thioguanin-GSK
- Thioguanin GSK
- ThioguaninGSK
|
Below are MeSH descriptors whose meaning is more general than "Thioguanine".
Below are MeSH descriptors whose meaning is more specific than "Thioguanine".
This graph shows the total number of publications written about "Thioguanine" by people in this website by year, and whether "Thioguanine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 3 | 1 | 4 |
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Below are the most recent publications written about "Thioguanine" by people in Profiles.
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6-Thioguanine Nucleotide Levels Are Associated With Mucosal Healing in Patients With Crohn's Disease. Inflamm Bowel Dis. 2018 11 29; 24(12):2621-2627.
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Porcine epidemic diarrhea virus papain-like protease 2 can be noncompetitively inhibited by 6-thioguanine. Antiviral Res. 2018 10; 158:199-205.
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Safety and feasibility of a low frame rate protocol for percutaneous coronary intervention to chronic total occlusions: preliminary experience. EuroIntervention. 2018 Aug 03; 14(5):e538-e545.
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6-Thioguanine inhibits rotavirus replication through suppression of Rac1 GDP/GTP cycling. Antiviral Res. 2018 08; 156:92-101.
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Thiopurines in Inflammatory Bowel Disease: New Findings and Perspectives. J Crohns Colitis. 2018 Apr 27; 12(5):610-620.
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Cost-utility Analysis: Thiopurines Plus Endoscopy-guided Biological Step-up Therapy is the Optimal Management of Postoperative Crohn's Disease. Inflamm Bowel Dis. 2017 11; 23(11):1930-1940.
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Thiopurines Dosed to a Therapeutic 6-Thioguanine Level in Combination with Adalimumab Are More Effective Than Subtherapeutic Thiopurine-based Combination Therapy or Adalimumab Monotherapy During Induction and Maintenance in Patients with Long-standing Crohn's Disease. Inflamm Bowel Dis. 2017 09; 23(9):1555-1565.
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Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus. Antiviral Res. 2015 Mar; 115:9-16.
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Thiopurine analogue inhibitors of severe acute respiratory syndrome-coronavirus papain-like protease, a deubiquitinating and deISGylating enzyme. Antivir Chem Chemother. 2009; 19(4):151-6.
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A 6-thioguanine nucleotide threshold level of 400 pmol/8 x 10(8) erythrocytes predicts azathioprine refractoriness in patients with inflammatory bowel disease and normal TPMT activity. Am J Gastroenterol. 2008 Dec; 103(12):3115-22.