"Receptors, CCR5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CCR receptors with specificity for CHEMOKINE CCL3; CHEMOKINE CCL4; and CHEMOKINE CCL5. They are expressed at high levels in T-LYMPHOCYTES; B-LYMPHOCYTES; MACROPHAGES; MAST CELLS; and NK CELLS. The CCR5 receptor is used by the HUMAN IMMUNODEFICIENCY VIRUS to infect cells.
| Descriptor ID |
D019713
|
| MeSH Number(s) |
D12.776.543.750.695.160.150.500 D12.776.543.750.705.852.125.150.500 D12.776.543.750.830.700.605
|
| Concept/Terms |
Receptors, CCR5- Receptors, CCR5
- CC-CKR5
- CCR5 Receptor
- Receptor, CCR5
- CCR5 Receptors
- Antigens, CD195
- CKR5 Receptors
- Receptors, CKR5
- CD195 Antigens
- CC Chemokine Receptor 5
|
Below are MeSH descriptors whose meaning is more general than "Receptors, CCR5".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Chemokine [D12.776.543.750.695.160]
- Receptors, CCR [D12.776.543.750.695.160.150]
- Receptors, CCR5 [D12.776.543.750.695.160.150.500]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Chemokine [D12.776.543.750.705.852.125]
- Receptors, CCR [D12.776.543.750.705.852.125.150]
- Receptors, CCR5 [D12.776.543.750.705.852.125.150.500]
- Receptors, Virus [D12.776.543.750.830]
- Receptors, HIV [D12.776.543.750.830.700]
- Receptors, CCR5 [D12.776.543.750.830.700.605]
Below are MeSH descriptors whose meaning is more specific than "Receptors, CCR5".
This graph shows the total number of publications written about "Receptors, CCR5" by people in this website by year, and whether "Receptors, CCR5" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 2 | 1 | 3 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 2 | 3 |
| 2013 | 2 | 1 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 2 | 2 | 4 |
| 2017 | 4 | 5 | 9 |
| 2018 | 12 | 11 | 23 |
| 2019 | 3 | 6 | 9 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, CCR5" by people in Profiles.
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Immune-Based Prediction of COVID-19 Severity and Chronicity Decoded Using Machine Learning. Front Immunol. 2021; 12:700782.
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Chronic Immune Activation and CD4+ T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy. Front Immunol. 2021; 12:693269.
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Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist. Sci Adv. 2021 06; 7(25).
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Variant-genetic and transcript-expression analysis showed a role for the chemokine-receptor CCR5 in COVID-19 severity. Int Immunopharmacol. 2021 Sep; 98:107825.
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Regulatory Noncoding and Predicted Pathogenic Coding Variants of CCR5 Predispose to Severe COVID-19. Int J Mol Sci. 2021 May 20; 22(10).
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CCR5Delta32 deletion as a protective factor in Czech first-wave COVID-19 subjects. Physiol Res. 2021 03 17; 70(1):111-115.
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CCR5?32 mutations do not determine COVID-19 disease course. Int J Infect Dis. 2021 Apr; 105:653-655.
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Does the CCR5-?32 mutation explain the variable coronavirus-2019 pandemic statistics in Europe? Croat Med J. 2020 12 31; 61(6):525-526.
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CCR5 ?32 minorallele is associated with susceptibility to SARS-CoV-2 infection and death: An epidemiological investigation. Clin Chim Acta. 2020 11; 510:60-61.
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Russian 'CRISPR-baby' scientist has started editing genes in human eggs with goal of altering deaf gene. Nature. 2019 10; 574(7779):465-466.