"Spermine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Descriptor ID |
D013096
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MeSH Number(s) |
D02.092.211.415.701.801.821 D02.092.782.802
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spermine".
Below are MeSH descriptors whose meaning is more specific than "Spermine".
This graph shows the total number of publications written about "Spermine" by people in this website by year, and whether "Spermine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spermine" by people in Profiles.
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SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals. Nat Commun. 2021 06 21; 12(1):3818.
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Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells. Int J Oncol. 2019 Jun; 54(6):2080-2094.
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Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses. J Virol. 2016 Nov 01; 90(21):9683-9692.
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The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress. Cancer Res. 2005 Nov 15; 65(22):10255-64.
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gamma-Glutamylamine derivatives in isolated rat hepatocyte proteins. Biochem J. 1988 Feb 01; 249(3):813-7.
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Determination of the polyamine content of rat heart mitochondria by the use of heparin-sepharose. Appl Biochem Biotechnol. 1985 Jun; 11(3):173-6.
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Urinary polyamine excretion in man. II. Influence of menstrual cycle. Biomedicine. 1980; 33(6):182-4.