"Spermidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
Descriptor ID |
D013095
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MeSH Number(s) |
D02.092.211.415.701.801 D02.092.782.677
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spermidine".
Below are MeSH descriptors whose meaning is more specific than "Spermidine".
This graph shows the total number of publications written about "Spermidine" by people in this website by year, and whether "Spermidine" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 |
2018 | 2 | 0 | 2 |
2019 | 1 | 2 | 3 |
2020 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spermidine" by people in Profiles.
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SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals. Nat Commun. 2021 06 21; 12(1):3818.
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Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses. Elife. 2020 12 15; 9.
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Chakrabartia godavariana gen. nov., sp. nov., a novel member of the family Sphingomonadaceae isolated from the Godavari River, India. Int J Syst Evol Microbiol. 2019 Aug; 69(8):2452-2458.
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Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells. Int J Oncol. 2019 Jun; 54(6):2080-2094.
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Reply to Gostner and Fuchs. Am J Clin Nutr. 2019 01 01; 109(1):218-219.
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Novel Beneficial Cardiovascular Effects of Natural Activators of Autophagy. Circ Res. 2018 09 28; 123(8):947-949.
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Spermidine-induced growth inhibition and apoptosis via autophagic activation in cervical cancer. Oncol Rep. 2018 Jun; 39(6):2845-2854.
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Induction of autophagy by spermidine promotes longevity. Nat Cell Biol. 2009 Nov; 11(11):1305-14.
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gamma-Glutamylamine derivatives in isolated rat hepatocyte proteins. Biochem J. 1988 Feb 01; 249(3):813-7.
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Determination of the polyamine content of rat heart mitochondria by the use of heparin-sepharose. Appl Biochem Biotechnol. 1985 Jun; 11(3):173-6.