"RNA Interference" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
| Descriptor ID |
D034622
|
| MeSH Number(s) |
G05.308.203.374.790
|
| Concept/Terms |
RNA Interference- RNA Interference
- Interference, RNA
- Gene Silencing, Post-Transcriptional
- Gene Silencing, Post Transcriptional
- RNA Silencing
- Post-Transcriptional Gene Silencing
- Post Transcriptional Gene Silencing
- Post-Transcriptional Gene Silencings
- Silencing, Post-Transcriptional Gene
- RNAi
- Posttranscriptional Gene Silencing
- Gene Silencing, Posttranscriptional
- Gene Silencings, Posttranscriptional
|
Below are MeSH descriptors whose meaning is more general than "RNA Interference".
Below are MeSH descriptors whose meaning is more specific than "RNA Interference".
This graph shows the total number of publications written about "RNA Interference" by people in this website by year, and whether "RNA Interference" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 2 | 1 | 3 |
| 2006 | 3 | 4 | 7 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 2 | 3 |
| 2010 | 2 | 2 | 4 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 3 | 3 |
| 2013 | 1 | 5 | 6 |
| 2014 | 0 | 4 | 4 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 5 | 5 |
| 2017 | 15 | 85 | 100 |
| 2018 | 6 | 53 | 59 |
| 2019 | 0 | 18 | 18 |
| 2020 | 4 | 7 | 11 |
| 2021 | 1 | 3 | 4 |
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Below are the most recent publications written about "RNA Interference" by people in Profiles.
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Virus-associated ribozymes and nano carriers against COVID-19. Artif Cells Nanomed Biotechnol. 2021 Dec; 49(1):204-218.
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SARS-CoV-2 infection induces the activation of tissue factor-mediated coagulation via activation of acid sphingomyelinase. Blood. 2021 07 29; 138(4):344-349.
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An isoform of Dicer protects mammalian stem cells against multiple RNA viruses. Science. 2021 07 09; 373(6551):231-236.
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SARS-CoV-2 Entry: At the Crossroads of CD147 and ACE2. Cells. 2021 06 08; 10(6).
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In silico analysis suggests the RNAi-enhancing antibiotic enoxacin as a potential inhibitor of SARS-CoV-2 infection. Sci Rep. 2021 05 13; 11(1):10271.
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Designing potential siRNA molecule for the nucleocapsid(N) gene silencing of different SARS-CoV-2 strains of Bangladesh: Computational approach. Comput Biol Chem. 2021 Jun; 92:107486.
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A small interfering RNA (siRNA) database for SARS-CoV-2. Sci Rep. 2021 04 23; 11(1):8849.
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RNAi Technology and Investigation on Possible Vaccines to Combat SARS-CoV-2 Infection. Appl Biochem Biotechnol. 2021 Jun; 193(6):1744-1756.
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Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions. Respir Res. 2021 Apr 06; 22(1):99.
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The SARS-CoV-2 receptor, angiotensin-converting enzyme 2, is required for human endometrial stromal cell decidualization†. Biol Reprod. 2021 02 11; 104(2):336-343.