"Mechlorethamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
| Descriptor ID |
D008466
|
| MeSH Number(s) |
D02.455.526.728.650.529
|
| Concept/Terms |
Mechlorethamine- Mechlorethamine
- Chlormethine
- Bis(2-chloroethyl)methylamine
- Mustine
- Nitrogen Mustard
- Chlorethazine
- Methylchlorethamine
Mechlorethamine Hydrochloride N-Oxide- Mechlorethamine Hydrochloride N-Oxide
- Hydrochloride N-Oxide, Mechlorethamine
- Mechlorethamine Hydrochloride N Oxide
- N-Oxide, Mechlorethamine Hydrochloride
Mechlorethamine N-Oxide- Mechlorethamine N-Oxide
- Mechlorethamine N Oxide
- Nitrogen Mustard N-Oxide
- N-Oxide, Nitrogen Mustard
- Nitrogen Mustard N Oxide
|
Below are MeSH descriptors whose meaning is more general than "Mechlorethamine".
Below are MeSH descriptors whose meaning is more specific than "Mechlorethamine".
This graph shows the total number of publications written about "Mechlorethamine" by people in this website by year, and whether "Mechlorethamine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mechlorethamine" by people in Profiles.
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The risk of second malignant tumors and its consequences for the overall survival of Hodgkin's disease patients and for the choice of their treatment at presentation: analysis of a series of 1524 cases consecutively treated at the Florence University Hospital. Int J Radiat Oncol Biol Phys. 2001 Apr 01; 49(5):1327-37.