alpha7 Nicotinic Acetylcholine Receptor
"alpha7 Nicotinic Acetylcholine Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the NICOTINIC ACETYLCHOLINE RECEPTOR subfamily of the LIGAND-GATED ION CHANNEL family. It consists entirely of pentameric α7 subunits expressed in the CNS, autonomic nervous system, vascular system, lymphocytes and spleen.
| Descriptor ID |
D064569
|
| MeSH Number(s) |
D12.776.157.530.400.400.100.500.500 D12.776.543.550.450.500.100.500.500 D12.776.543.585.400.500.100.500.500 D12.776.543.750.130.687.500 D12.776.543.750.720.360.550.500
|
| Concept/Terms |
Receptor, alpha-Bungarotoxin- Receptor, alpha-Bungarotoxin
- Receptor, alpha Bungarotoxin
- alpha-Bungarotoxin Receptor
- alpha-Bungarotoxin Receptors
- Receptors, alpha-Bungarotoxin
- alpha Bungarotoxin Receptors
|
Below are MeSH descriptors whose meaning is more general than "alpha7 Nicotinic Acetylcholine Receptor".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Nicotinic [D12.776.157.530.400.400.100.500]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.157.530.400.400.100.500.500]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, Nicotinic [D12.776.543.550.450.500.100.500]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.550.450.500.100.500.500]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Nicotinic [D12.776.543.585.400.500.100.500]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.585.400.500.100.500.500]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, Nicotinic [D12.776.543.750.130.687]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.750.130.687.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Nicotinic [D12.776.543.750.720.360.550]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.750.720.360.550.500]
Below are MeSH descriptors whose meaning is more specific than "alpha7 Nicotinic Acetylcholine Receptor".
This graph shows the total number of publications written about "alpha7 Nicotinic Acetylcholine Receptor" by people in this website by year, and whether "alpha7 Nicotinic Acetylcholine Receptor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 4 | 1 | 5 |
| 2018 | 5 | 2 | 7 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 3 | 0 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "alpha7 Nicotinic Acetylcholine Receptor" by people in Profiles.
-
From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the dysregulated inflammation in COVID-19? J Immunotoxicol. 2021 12; 18(1):23-29.
-
Regulation of the acetylcholine/a7nAChR anti-inflammatory pathway in COVID-19 patients. Sci Rep. 2021 06 04; 11(1):11886.
-
SARS-Cov-2 spike protein fragment 674-685 protects mitochondria from releasing cytochrome c in response to apoptogenic influence. Biochem Biophys Res Commun. 2021 07 05; 561:14-18.
-
Is SARS-CoV-2 Spike glycoprotein impairing macrophage function via a7-nicotinic acetylcholine receptors? Food Chem Toxicol. 2021 Jun; 152:112184.
-
E-cigarette vape and lung ACE2 expression: Implications for coronavirus vulnerability. Environ Toxicol Pharmacol. 2021 Aug; 86:103656.
-
Nicotinic cholinergic system and COVID-19: In silico identification of interactions between a7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V and SARS-CoV-2 Spike glycoproteins. Food Chem Toxicol. 2021 Mar; 149:112009.
-
Nicotine Changes Airway Epithelial Phenotype and May Increase the SARS-COV-2 Infection Severity. Molecules. 2020 Dec 28; 26(1).
-
The a7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function. Mol Med. 2020 10 30; 26(1):98.
-
E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR a7 receptor: role of nAChR a7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation. Respir Res. 2020 Jun 18; 21(1):154.
-
Cytokine Release Syndrome (CRS) and Nicotine in COVID-19 Patients: Trying to Calm the Storm. Front Immunol. 2020; 11:1359.