Protein Structure, Tertiary
"Protein Structure, Tertiary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The level of protein structure in which combinations of secondary protein structures (ALPHA HELICES; BETA SHEETS; loop regions, and AMINO ACID MOTIFS) pack together to form folded shapes. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure.
| Descriptor ID |
D017434
|
| MeSH Number(s) |
G02.111.570.820.709.610
|
| Concept/Terms |
Protein Structure, Tertiary- Protein Structure, Tertiary
- Tertiary Protein Structure
- Protein Structures, Tertiary
- Tertiary Protein Structures
|
Below are MeSH descriptors whose meaning is more general than "Protein Structure, Tertiary".
Below are MeSH descriptors whose meaning is more specific than "Protein Structure, Tertiary".
This graph shows the total number of publications written about "Protein Structure, Tertiary" by people in this website by year, and whether "Protein Structure, Tertiary" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 13 | 13 |
| 2004 | 0 | 12 | 12 |
| 2005 | 0 | 13 | 13 |
| 2006 | 0 | 27 | 27 |
| 2007 | 0 | 11 | 11 |
| 2008 | 0 | 10 | 10 |
| 2009 | 1 | 10 | 11 |
| 2010 | 0 | 14 | 14 |
| 2011 | 1 | 10 | 11 |
| 2012 | 0 | 4 | 4 |
| 2013 | 0 | 16 | 16 |
| 2014 | 0 | 10 | 10 |
| 2015 | 0 | 6 | 6 |
| 2016 | 0 | 8 | 8 |
| 2017 | 0 | 33 | 33 |
| 2018 | 0 | 8 | 8 |
| 2019 | 0 | 3 | 3 |
| 2020 | 0 | 17 | 17 |
| 2021 | 0 | 14 | 14 |
To return to the timeline, click here.
Below are the most recent publications written about "Protein Structure, Tertiary" by people in Profiles.
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Rapidly emerging SARS-CoV-2 B.1.1.7 sub-lineage in the United States of America with spike protein D178H and membrane protein V70L mutations. Emerg Microbes Infect. 2021 Dec; 10(1):1293-1299.
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Characteristics of Angiotensin I-converting enzyme 2, type II transmembrane serine protease 2 and 4 in tree shrew indicate it as a potential animal model for SARS-CoV-2 infection. Bioengineered. 2021 12; 12(1):2836-2850.
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SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity. J Biol Chem. 2021 10; 297(4):101127.
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SARS-CoV-2 B.1.617 Indian variants: Are electrostatic potential changes responsible for a higher transmission rate? J Med Virol. 2021 Dec; 93(12):6551-6556.
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Regulated Intramembrane Proteolysis of ACE2: A Potential Mechanism Contributing to COVID-19 Pathogenesis? Front Immunol. 2021; 12:612807.
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Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants' spike protein-an in silico analysis. PLoS One. 2021; 16(5):e0251426.
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SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains. PLoS One. 2021; 16(5):e0251368.
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Computational study of the therapeutic potentials of a new series of imidazole derivatives against SARS-CoV-2. J Pharmacol Sci. 2021 Sep; 147(1):62-71.
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Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2. Cell Chem Biol. 2021 06 17; 28(6):855-865.e9.
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High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein Cell. 2021 11; 12(11):877-888.