"Molecular Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic three-dimensional shape of a molecule.
| Descriptor ID |
D008968
|
| MeSH Number(s) |
G02.111.570.820
|
| Concept/Terms |
Molecular Conformation- Molecular Conformation
- Conformation, Molecular
- Conformations, Molecular
- Molecular Conformations
- Three Dimensional Molecular Structure
- Molecular Configuration
- Molecular Structure, Three Dimensional
- 3D Molecular Structure
- 3D Molecular Structures
- Molecular Structure, 3D
- Molecular Structures, 3D
- Structure, 3D Molecular
- Structures, 3D Molecular
- Configuration, Molecular
- Configurations, Molecular
- Molecular Configurations
|
Below are MeSH descriptors whose meaning is more general than "Molecular Conformation".
Below are MeSH descriptors whose meaning is more specific than "Molecular Conformation".
This graph shows the total number of publications written about "Molecular Conformation" by people in this website by year, and whether "Molecular Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 25 | 27 |
| 2018 | 0 | 27 | 27 |
| 2019 | 0 | 10 | 10 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Molecular Conformation" by people in Profiles.
-
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors. Proc Natl Acad Sci U S A. 2021 09 07; 118(36).
-
The nucleotide addition cycle of the SARS-CoV-2 polymerase. Cell Rep. 2021 08 31; 36(9):109650.
-
Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing. Structure. 2021 12 02; 29(12):1382-1396.e6.
-
3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. J Med Chem. 2022 02 24; 65(4):2926-2939.
-
Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease. J Med Chem. 2021 07 22; 64(14):10047-10058.
-
The role of the envelope protein in the stability of a coronavirus model membrane against an ethanolic disinfectant. J Chem Phys. 2021 Jun 28; 154(24):245101.
-
Anti-Inflammatory, Antiallergic, and COVID-19 Main Protease (Mpro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus terreus. Molecules. 2021 Jun 02; 26(11).
-
Similarities and differences in the conformational stability and reversibility of ORF8, an accessory protein of SARS-CoV-2, and its L84S variant. Biochem Biophys Res Commun. 2021 07 23; 563:92-97.
-
Synthesis, molecular docking, and in silico ADMET studies of 4-benzyl-1-(2,4,6-trimethyl-benzyl)-piperidine: Potential Inhibitor of SARS-CoV2. Bioorg Chem. 2021 07; 112:104967.
-
Discovery of anti-infective adipostatins through bioactivity-guided isolation and heterologous expression of a type III polyketide synthase. Bioorg Chem. 2021 07; 112:104925.