Receptors, N-Methyl-D-Aspartate
"Receptors, N-Methyl-D-Aspartate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
| Descriptor ID |
D016194
|
| MeSH Number(s) |
D12.776.157.530.400.400.500.500 D12.776.543.550.450.500.200.500 D12.776.543.585.400.500.200.500 D12.776.543.750.720.200.450.400.500
|
| Concept/Terms |
Receptors, N-Methyl-D-Aspartate- Receptors, N-Methyl-D-Aspartate
- Receptors, N Methyl D Aspartate
- N-Methyl-D-Aspartate Receptors
- N Methyl D Aspartate Receptors
- NMDA Receptors
- Receptors, N-Methylaspartate
- Receptors, N Methylaspartate
- Receptors, NMDA
- NMDA Receptor-Ionophore Complex
- NMDA Receptor Ionophore Complex
- N-Methylaspartate Receptors
- N Methylaspartate Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, N-Methyl-D-Aspartate".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Receptors, Ionotropic Glutamate [D12.776.157.530.400.400.500]
- Receptors, N-Methyl-D-Aspartate [D12.776.157.530.400.400.500.500]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Receptors, Ionotropic Glutamate [D12.776.543.550.450.500.200]
- Receptors, N-Methyl-D-Aspartate [D12.776.543.550.450.500.200.500]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Receptors, Ionotropic Glutamate [D12.776.543.585.400.500.200]
- Receptors, N-Methyl-D-Aspartate [D12.776.543.585.400.500.200.500]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, Glutamate [D12.776.543.750.720.200.450]
- Receptors, Ionotropic Glutamate [D12.776.543.750.720.200.450.400]
- Receptors, N-Methyl-D-Aspartate [D12.776.543.750.720.200.450.400.500]
Below are MeSH descriptors whose meaning is more specific than "Receptors, N-Methyl-D-Aspartate".
This graph shows the total number of publications written about "Receptors, N-Methyl-D-Aspartate" by people in this website by year, and whether "Receptors, N-Methyl-D-Aspartate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 6 | 5 | 11 |
| 2018 | 4 | 6 | 10 |
| 2019 | 1 | 2 | 3 |
| 2020 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, N-Methyl-D-Aspartate" by people in Profiles.
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Palilalia as a prominent feature of anti-NMDA receptor encephalitis in a woman with COVID-19. J Neurol. 2021 Nov; 268(11):3995-3997.
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Ifenprodil Stereoisomers: Synthesis, Absolute Configuration, and Correlation with Biological Activity. J Med Chem. 2021 01 28; 64(2):1170-1179.
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Opsoclonus After COVID-19 in an Infant. Pediatr Neurol. 2021 04; 117:34.
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Neurological Involvements of SARS-CoV2 Infection. Mol Neurobiol. 2021 Mar; 58(3):944-949.
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N-Methyl-d-Aspartate Receptor Encephalitis Associated With COVID-19 Infection in a Toddler. Pediatr Neurol. 2021 01; 114:75-76.
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The potential role of inflammation reaction in COVID-19 related posttraumatic stress disorder. Asian J Psychiatr. 2020 Dec; 54:102405.
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Anti-NMDA receptor encephalitis in a psychiatric Covid-19 patient: A case report. Brain Behav Immun. 2020 07; 87:179-181.
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Behavioral, circuitry, and molecular aberrations by region-specific deficiency of the high-risk autism gene Cul3. Mol Psychiatry. 2021 05; 26(5):1491-1504.
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Lateral Habenular Burst Firing as a Target of the Rapid Antidepressant Effects of Ketamine. Trends Neurosci. 2019 03; 42(3):179-191.
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Down syndrome: Neurobiological alterations and therapeutic targets. Neurosci Biobehav Rev. 2019 03; 98:234-255.