1-Phosphatidylinositol 4-Kinase
"1-Phosphatidylinositol 4-Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of phosphatidylinositol (PHOSPHATIDYLINOSITOLS) to phosphatidylinositol 4-phosphate, the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.
| Descriptor ID |
D019870
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| MeSH Number(s) |
D08.811.913.696.620.550
|
| Concept/Terms |
1-Phosphatidylinositol 4-Kinase- 1-Phosphatidylinositol 4-Kinase
- 1 Phosphatidylinositol 4 Kinase
- Phosphoinositide Kinase
- Kinase, Phosphoinositide
- Phosphatidylinositiol Kinase
- Kinase, Phosphatidylinositiol
- Phosphatidylinositol 4-Kinase
- Phosphatidylinositol 4 Kinase
- PI 4-Kinase
- PI 4 Kinase
- Phosphatidylinositol Kinase Type II
- PtdIns 4-Kinase
- PtdIns 4 Kinase
|
Below are MeSH descriptors whose meaning is more general than "1-Phosphatidylinositol 4-Kinase".
Below are MeSH descriptors whose meaning is more specific than "1-Phosphatidylinositol 4-Kinase".
This graph shows the total number of publications written about "1-Phosphatidylinositol 4-Kinase" by people in this website by year, and whether "1-Phosphatidylinositol 4-Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "1-Phosphatidylinositol 4-Kinase" by people in Profiles.
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Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIß) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses. ChemMedChem. 2021 12 06; 16(23):3548-3552.
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Identification of novel Plasmodium falciparum PI4KB inhibitors as potential anti-malarial drugs: Homology modeling, molecular docking and molecular dynamics simulations. Comput Biol Chem. 2019 Jun; 80:79-89.
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PI4KIII inhibitor enviroxime impedes the replication of the hepatitis C virus by inhibiting PI3 kinases. J Antimicrob Chemother. 2018 12 01; 73(12):3375-3384.
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Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIß (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology. J Med Chem. 2017 01 12; 60(1):100-118.