"Adherens Junctions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Anchoring points where the CYTOSKELETON of neighboring cells are connected to each other. They are composed of specialized areas of the plasma membrane where bundles of the ACTIN CYTOSKELETON attach to the membrane through the transmembrane linkers, CADHERINS, which in turn attach through their extracellular domains to cadherins in the neighboring cell membranes. In sheets of cells, they form into adhesion belts (zonula adherens) that go all the way around a cell.
| Descriptor ID |
D022005
|
| MeSH Number(s) |
A11.284.149.165.420.020
|
| Concept/Terms |
Adherens Junctions- Adherens Junctions
- Adherens Junction
- Junction, Adherens
- Junctions, Adherens
|
Below are MeSH descriptors whose meaning is more general than "Adherens Junctions".
Below are MeSH descriptors whose meaning is more specific than "Adherens Junctions".
This graph shows the total number of publications written about "Adherens Junctions" by people in this website by year, and whether "Adherens Junctions" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Adherens Junctions" by people in Profiles.
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A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress. Dev Cell. 2018 11 19; 47(4):439-452.e6.
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The silent healer: miR-205-5p up-regulation inhibits epithelial to mesenchymal transition in colon cancer cells by indirectly up-regulating E-cadherin expression. Cell Death Dis. 2018 01 19; 9(2):66.
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Regulated recruitment of SRGAP1 modulates RhoA signaling for contractility during epithelial junction maturation. Cytoskeleton (Hoboken). 2018 02; 75(2):61-69.
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Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1. Nat Commun. 2017 10 05; 8(1):790.
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Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins. Cell Stem Cell. 2017 09 07; 21(3):349-358.e6.
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Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis. Ann Rheum Dis. 2017 Jun; 76(6):1123-1132.
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ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Mol Biol Cell. 2017 01 01; 28(1):12-20.
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Structural alteration of tight and adherens junctions in villous and crypt epithelium of the small and large intestine of conventional nursing piglets infected with porcine epidemic diarrhea virus. Vet Microbiol. 2015 Jun 12; 177(3-4):373-8.
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Intercalated disc abnormalities, reduced Na(+) current density, and conduction slowing in desmoglein-2 mutant mice prior to cardiomyopathic changes. Cardiovasc Res. 2012 Sep 01; 95(4):409-18.